Health & Medicinearticle2026-09-09

From Biological Insight to a New Class of Medicines for Hemophilia A

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Abstract

In this Perspective, the 2026 Lasker-DeBakey Clinical Medical Research Award winners describe the development of a bispecific antibody that mimics blood coagulation factor VIII, revolutionizing the treatment of hemophilia, a life-threatening bleeding disorder caused by lack of factor VIII.

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View paper (DOI)OpenAlexJAMAPublished 2026-09-09

Authors: Kunihiro Hattori, Takehisa Kitazawa, Tomoyuki Igawa

Institutions: Saitama International Medical Center, Osaka Prefectural Toyonaka Support School