Health & Medicinearticle2026-09-02

Computed Tomography Reconstruction Algorithm Using Markov Random Field Model

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Abstract

X-ray computed tomography (CT) reveals the materials’ internal structures non-destructively from a tilt series of projected images. Filtered back projection (FBP) is a widely-adopted reconstruction algorithm in CT owing to its small computational cost. Under low-dose or sparse-view conditions, however, FBP often amplifies noise, severely degrading the reconstructed images. In this study, we evaluated the performance of a Bayesian CT reconstruction algorithm based on the Markov random field model under such adverse conditions. Through simulations, we demonstrated that the proposed algorithm shows higher reconstruction performance than FBP under both low-dose and sparse-view conditions. The hyperparameters are estimated by minimizing the Bayesian free energy, enabling adaptive reconstruction that reflects the noise characteristics of the observed projected image. These results suggest that the proposed algorithm can broaden the applicability of CT to dose-sensitive applications and time-constrained measurements, where only limited observed projected images are available.

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View paper (DOI)Open access versionOpenAlexJournal of the Physical Society of JapanPublished 2026-09-02

Authors: Taiga Shimomiya, Taichi Kusumi, Masayuki Uesugi, Akihisa Takeuchi, Yuki Sada, Hayaru Shouno, Masato Okada

Institutions: The University of Tokyo, Japan Synchrotron Radiation Research Institute, University of Electro-Communications