Neurocutaneous Axis in Atopic Dermatitis

Abstract

This research paper examines the connection between Atopic Dermatitis and the nervous system through the concept of the "Neurocutaneous Axis." It highlights how psychological stress worsens AD symptoms by triggering neuro-immune responses, while chronic itch and sleep loss increase anxiety and depression. The paper concludes that effective management requires a multimodal approach targeting both skin inflammation and the psychological factors driving the disease.