The Binding of Methyl Mercury and DNA
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Abstract
A method for the quantitative measurement of methyl mercury (CH3Hg+) was developed in addition to a method for the quantitative study of the binding of CH3Hg+ to DNA. Preliminary results seem to indicate that CH3Hg+ binds to DNA; [CH3Hg+]/[DNA] bound reaches a maximum as [CH3Hg+] is increased. It also appears that more CH3Hg+ is bound to denatured DNA than to native DNA.
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Authors: Michael Morris Rosbash
Institutions: California Institute of Technology