Spiro-helicenoidCarbofluoresceins: CPL-Active Emittersfor Bioimaging
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Abstract
Abstract Chiral fluorescent probes based on small organic molecules present a promising platform for advanced bioimaging applications. In this work, we have developed a helically chiral spiro-shaped carbofluorescein with red emission (λem ≤ 613 nm). Configurationally stable enantiomers were separated, and electronic circular dichroism (ECD) and circularly polarized luminescence (CPL) evaluated. Preliminary results showed cellular permeability and intracellular emission.
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Authors: Laura Erviti-Marticorena, Silvia Simón‐Fuente, Sandra Míguez‐Lago, José M. Paredes, M. Ribagorda, María D. Girón, Alba Millán, Juan M. Cuerva, D. Miguel
Institutions: Universidad de Granada, Universidad Autónoma de Madrid