Real-World Experience of Hepatitis C Treatment With Glecaprevir-Pibrentasvir During Pregnancy.
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Abstract
Guidelines endorse antenatal hepatitis C virus treatment following shared decision making. No clinical trial or real-world data exist for glecaprevir-pibrentasvir (GLE/PIB). We report our experience with prenatal GLE/PIB in 14 patients. Ten patients completed treatment; all achieved virologic response by or at delivery, with no maternal or neonatal safety concerns.
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Authors: L Madeline McCrary, Megan R Curtis, Jeannie C Kelly, Jessica Elrod-Gallegos, Patrick Kojima, Patricia Werner, Jennifer L. Mullersman, Tracey Habrock-Bach, Michael J. Durkin, Laura R. Marks
Institutions: Washington University in St. Louis, University of Missouri–St. Louis, John Cochran VA Medical Center