Research Briefs

Biochemistry, Genetics and Molecular Biology · Molecular Biology

vaccines and immunoinformatics approaches

Log in to follow
Abstract editorial illustration accompanying the article: AI and docking agreed in some drug screens, but not all
AI & Computing

AI and docking agreed in some drug screens, but not all

Researchers evaluated three AI systems on hundreds of molecules bound to a SARS-CoV-2 protein and in three prospective drug screens. The results suggest that combining AI-based predictions with traditional docking may help prioritize candidates, although no single approach worked best in every test.

·50 views
Abstract editorial illustration accompanying the article: Predicting which peptides T cells recognize remains difficult for AI
Biology

Predicting which peptides T cells recognize remains difficult for AI

AI tools for predicting T-cell recognition often struggle when the peptide has not appeared in their training data. A study of structure-based classifiers found that extra training objectives can improve predictions for unfamiliar peptides, but the broader generalization problem remains.

·64 views