Medicine · Pediatrics, Perinatology and Child Health

Pediatric Urology and Nephrology Studies

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Abstract editorial illustration accompanying the article: New guideline updates urinary infection guidance for children ages 8 days to 5 years
Health & Medicine
High evidenceReview

New guideline updates urinary infection guidance for children ages 8 days to 5 years

This clinical practice guideline updates earlier guidance on urinary tract infections in children from 8 days through 5 years of age. It reviews evidence and provides recommendations for evaluation, antibiotic treatment, imaging, and assessment of related conditions. The guideline reports that most key recommendations are based on low or very low certainty evidence.

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Abstract editorial illustration accompanying the article: Review finds uncertainty about molecular testing for urinary infections
Health & Medicine
High evidenceReview

Review finds uncertainty about molecular testing for urinary infections

A systematic review examined 12 studies of molecular tests for urinary tract infections in adults, including two randomized trials with 830 participants. The review found that PCR-based tests were more sensitive than standard urine cultures and were linked with short-term symptom improvement in both trials, but the tests were less specific and the overall clinical evidence remains limited.

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Abstract editorial illustration accompanying the article: Researchers define signs of fever-related discomfort in children
Health & Medicine
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Researchers define signs of fever-related discomfort in children

An international Delphi consensus panel developed a proposed definition and assessment framework for discomfort linked to fever in children. The framework describes discomfort as involving behavioral, emotional, and functional signs and groups severity into green, amber, and red categories. It is expert-derived and has not yet been validated in larger or more diverse groups of children.

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