Research Briefs

Medicine · Endocrinology, Diabetes and Metabolism

Menopause: Health Impacts and Treatments

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Abstract editorial illustration accompanying the article: Study links earlier menopausal changes at 46 with anxiety and depression symptoms
Health & Medicine
Moderate evidenceHuman study

Study links earlier menopausal changes at 46 with anxiety and depression symptoms

Researchers studied 2,632 women from a Finnish birth cohort to examine whether being classified as climacteric at age 46 was associated with anxiety, depression symptoms, and psychiatric medication purchases. Climacteric women had higher reported levels of some anxiety and depression symptoms than preclimacteric women, although this observational study cannot show that menopausal changes caused those symptoms.

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Health & Medicine
Moderate evidenceReview

Review finds limited evidence for vaginal laser in breast cancer survivors

A scoping review examined vaginal fractional CO₂ laser therapy for genitourinary syndrome of menopause, a group of vaginal and urinary symptoms, among women with current or previous breast cancer. Across 22 reports involving approximately 1,099 participant observations, observational studies often reported symptom improvements, but two sham-controlled randomized trials did not find a clinically meaningful benefit over sham treatment. The findings are informational and do not establish whether this therapy is effective or safe over the long term.

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