Health & Medicine
Moderate evidenceReview
Review compares epigenetic drugs with chemotherapy in relapsed T-cell lymphoma
This meta-analysis examined 38 studies involving 2,170 people with relapsed or treatment-resistant peripheral T-cell lymphoma. Regimens containing an epigenetic drug had tumor response rates similar to conventional chemotherapy, but the studies reported higher one-year progression-free and overall survival rates with the epigenetic-containing regimens. Because the comparisons were based mainly on separate cohorts rather than randomized trials, the results show an association rather than proof that one approach caused better outcomes.
·25 views
