Research Briefs

Medicine · Cardiology and Cardiovascular Medicine

Heart Rate Variability and Autonomic Control

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Abstract editorial illustration accompanying the article: New analysis finds small QTc changes with some antidepressants early in treatment
Health & Medicine
High evidenceReview

New analysis finds small QTc changes with some antidepressants early in treatment

Researchers analysed double-blind randomised trials of adults with major depressive disorder to compare 10 antidepressants with placebo during the first eight weeks of treatment. Some medicines were associated with longer QTc intervals, a heart rhythm measurement, but the analysis did not find higher rates of early major cardiovascular events or non-suicidal death compared with placebo.

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Abstract editorial illustration accompanying the article: Vagus-nerve stimulation may reduce pain and fatigue in rheumatic diseases
Biology

Vagus-nerve stimulation may reduce pain and fatigue in rheumatic diseases

A review of research on vagus-nerve stimulation found reports of lower inflammatory activity and fewer pro-inflammatory cytokines in rheumatic diseases. The studies also reported possible reductions in pain, fatigue and disease activity, although their small size and differing methods limit the conclusions.

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