Biochemistry, Genetics and Molecular Biology · Genetics

Genomic variations and chromosomal abnormalities

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Abstract editorial illustration accompanying the article: Sister copies of human chromosomes are not arranged exactly alike

Sister copies of human chromosomes are not arranged exactly alike

Researchers found that sister copies of human chromosomes have a previously unrecognized difference in their large-scale three-dimensional arrangement. The shift is linked to the protein complexes that hold the copies together and could affect how cells find matching DNA during repair.

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