Zimmer Biomet (Netherlands)

Disease Duration Differentiates Freezing of Gait Response to Subthalamic and Nigral Stimulation for Parkinson's Disease in an Exploratory Multicenter Controlled Trial

BACKGROUND: Freezing of gait (FoG) belongs to most pressing unmet symptoms in the treatment of Parkinson's disease. OBJECTIVES: To explore whether combined subthalamic and nigral (STN + SNr) deep brain stimulation improves FoG compared with optimized STN stimulation alone; to ide...

Healthcare Utilization and Direct Medical Costs of Hepatocellular Carcinoma Treatment — A German Claims Data Study of 2778 Patients

Hepatocellular carcinoma (HCC) is a cancer with rising incidence and economic burden. However, evidence on healthcare resource utilization (HCRU) and associated costs is scarce in Europe. This study aims to determine HCRU and costs of HCC from a German third-party payer's perspec...

Estimation and Bias Adjustment of Regional Mortality Rates with Incomplete Information—The Case of German Federal States

Reliable regional mortality rates are crucial for public health monitoring and planning. However, their estimation is often complicated by data limitations, with data being published only in broad age groups or affected by systematic errors. This is particularly relevant in inter...

Global Research Trends on Campylobacter spp. and Human Health: A bibliometric analysis (2017–2025)

<ns5:p> Background Campylobacter spp. is among the leading causes of foodborne gastroenteritis worldwide, with infections caused by Campylobacter jejuni and Campylobacter coli the most common. These infections pose a major challenge to global public health. Despite the recent inc...

Procalcitonin as a predictor of length of stay in patients with odontogenic infections

OBJECTIVES: Our study aimed to evaluate procalcitonin (PCT) as a prognostic marker in advanced odontogenic infections. In addition, we sought to identify further prognostic markers that could be used to predict the length of hospital stay (LOS). MATERIALS AND METHODS: We retrospe...

Renal Resistive Index Responsiveness to a Mean Arterial Pressure Test As a Guide for Mean Arterial Pressure Target in the Early Phase of Septic Shock: A Physiological Study

OBJECTIVES: Guidelines recommend targeting a mean arterial pressure (MAP) greater than or equal to 65 mm Hg in septic shock. Although experts advocate for individualized targets, no validated bedside tool exists. An increased renal resistive index (RRI) is associated with acute k...