Ziekenhuis Oost-Limburg

Biventricular vs conduction system pacing after atrioventricular node ablation for heart failure with atrial fibrillation: the CONDUCT-AF trial.

BACKGROUND AND AIMS: Randomized evidence comparing conduction system pacing (CSP) and biventricular pacing (BVP) following atrioventricular node ablation in patients with refractory atrial fibrillation (AF) and heart failure (HF) remains limited. This study evaluated whether CSP...

Premedication practices prior to neonatal laryngoscopy: a nationwide observational study in Belgian NICUs

Intubation or less invasive surfactant administration (LISA) in neonates both require laryngoscopy, a stressful and painful procedure. This study aimed to document premedication practices before laryngoscopy in Belgium and explore reasons for absence of premedication. Sub-analysi...

Bacterial orbital infection leading to orbital exenteration: a case series

Orbital exenteration (OE) secondary to infection is rare. This case series reports 3 cases and aims to elucidate the possible underlying etiopathogenesis. A retrospective data analysis was performed of patients who underwent an OE and subsequently received an orbital prosthesis f...

A multicenter randomized, double-blinded placebo-controlled phase 2 trial to evaluate safety and efficacy of ilofotase alfa in patients at risk for kidney injury following open heart surgery

Acute impairment of kidney function after cardiac surgery is common and associated with an increased morbidity and mortality. Ilofotase alfa has demonstrated potential to attenuate renal injury through its immunomodulatory effects. We evaluated the safety and efficacy of ilofotas...

Timing of PCI in Patients Undergoing Transcatheter Aortic-Valve Implantation

BackgroundApproximately one half of patients undergoing transcatheter aortic-valve implantation (TAVI) have concomitant coronary artery disease. Although percutaneous coronary intervention (PCI) is often performed before TAVI, the preferred treatment strategy has not been establi...

Feasibility of radiomics and deep learning methods for prognosis of non–small cell lung cancer using 18F-FDG PET/CT

Accurate prognostication for non-small cell lung cancer (NSCLC) is challenging due to tumor heterogeneity and the limitations of conventional PET biomarkers. This technical feasibility study compared the difference in prognostic performance of radiomics and deep learning (CNN) me...

StereoBed - salvage stereotactic body radiotherapy of the prostate bed for biochemical recurrence after radical prostatectomy: study protocol for a randomized phase II/III trial

In cases of biochemical recurrence (BCR) after radical prostatectomy, salvage radiotherapy (RT) is a well-established standard-of-care treatment. Stereotactic body radiotherapy (SBRT) may offer a shorter treatment duration and favorable radiobiological characteristics, but eviden...