Zhongshan Hospital of Xiamen University

Global and regional brain-age gaps in primary trigeminal neuralgia: a cross-sectional structural MRI study of 133 anatomical structures

Primary trigeminal neuralgia (TN) is a severe craniofacial neuropathic pain disorder. Quantitative magnetic resonance imaging (MRI) studies suggest that TN-related alterations may extend beyond the trigeminal pathways. The brain-age gap (BAG) is MRI-predicted brain age minus chro...

Vibratory Characteristics and Quantitative Parameters of Laryngeal Dystonia: A Scoping Review of High‐Speed Videoendoscopy Studies

ABSTRACT Objective To review the clinical application and quantitative parameters of high‐speed videoendoscopy (HSV) in evaluating vocal fold kinematics in patients with laryngeal dystonia (LD), to summarize the limitations of existing studies, and to provide a reference for futu...

Risk factors and prevalence of incontinence-associated dermatitis in elderly patients: a meta-analysis and systematic review

This systematic review aimed to evaluate the prevalence and risk factors of Incontinence-Associated Dermatitis (IAD) in elderly patients. A systematic search was conducted across 10 databases, including PubMed, Embase, Web of Science, Cochrane Library, CINAHL, Ovid MEDLINE, Scopu...

Two-wave modified cardiometabolic index change patterns and incident edentulism in Chinese adults: a longitudinal study from CHARLS

Abstract Objectives Complete tooth loss is a late-stage oral health endpoint that may reflect cumulative oral, systemic, behavioral, and social risk processes. We examined whether two-wave patterns of the modified cardiometabolic index (MCMI) from 2011 to 2015 were associated wit...

Comparative efficacy of irrigation activation systems in root canal cleanliness: a region-specific analysis of debris and smear layer removal

This study aimed to compare the efficacy of four irrigation activation systems against conventional needle irrigation (CNI) in removing debris and smear layer from root canal. Forty human single-rooted teeth premolars were instrumented to a consistent size and randomly divided in...

Red blood cell distribution width and 28 days mortality in sepsis-associated delirium: a multicenter study and machine learning analyses

The specific prognostic relevance of red blood cell distribution width (RDW) regarding sepsis-associated delirium (SAD) remains poorly understood. Data were retrieved from the MIMIC-IV and eICU-CRD registries. Kaplan–Meier curves, multivariable Cox regression, restricted cubic sp...

Surface morphology, printing accuracy and flexural strength of 3D-printed zirconia posts with longitudinal microgrooves

Postcore restoration is essential for compromised teeth. Zirconia is a promising material due to its esthetics, strength, and radiopacity. Additive manufacturing, particularly advanced customized jetting (ACJ) technology, enables the fabrication of complex microstructures on zirc...

Artificial intelligence empowers full-stack histopathological diagnosis and prognosis of renal cell tumor: a multi-center study with external validation

BACKGROUND: The rapid advancement of digital pathology has opened unprecedented opportunities for intelligent diagnosis in renal cell tumor. However, there remains a significant gap in the availability of reliable deep learning models capable of comprehensive kidney cancer detect...

METTL14-dependent N6-methyladenosine modification of FGF16 participates in IGFBP5 deficiency-enhanced angiogenesis

Abstract N 6 -methyladenosine (m 6 A) RNA modification plays critical roles in physiological and pathological processes. Our prior study demonstrated that IGFBP5 expression is upregulated in the ischemic limb, whereas endothelial-specific IGFBP5 knockout (Igfbp5 EKO ) protects ag...

METTL14-dependent N6-methyladenosine modification of FGF16 participates in IGFBP5 deficiency-enhanced angiogenesis.

A-FGF16 axis may offer novel therapeutic strategies for ischemic disease.

Diagnostic accuracy, time window estimation, and prognostic value of diffusion-weighted MRI in acute ischemic stroke: a systematic review and meta-analysis

Diffusion-weighted imaging (DWI) is central to acute ischemic stroke (AIS) management; however, its performance varies across different clinical applications. This systematic review and meta-analysis comprehensively evaluated the diagnostic accuracy, time window estimation capabi...

Gliomas grading prediction using multicenter 3T Magnetic Resonance Spectroscopy

Abstract Background Magnetic Resonance Spectroscopy (MRS) is a non-invasive imaging technique that detects various metabolites in brain tissues, making it essential for the grading of brain gliomas. MRS measures key metabolites such as N-acetyl-aspartate (NAA), choline (Cho), and...