Zhejiang Shuren University

MesoScreen: A Computational Platform Providing Unified Data for Liquid-Crystal Research

The development of advanced liquid-crystal (LC) materials requires reliable and standardized structure–property data, yet generating such data through molecular simulation remains time-consuming and technically demanding. Here, we present MesoScreen, an online computational platf...

Catalyst or Constraint? Direct Impacts and Spillovers of China’s E-Commerce Policy on Urban Spatial Restructuring via Nighttime Light Decomposition

Digital industrial policies are increasingly used to promote economic restructuring and spatial reorganization, yet their effects on urban spatial structure remain poorly understood. This study examines whether China’s National E-commerce Demonstration City (NEDC) policy acts as...

AI tools drive innovation in sports firms through employee experiences moderated by perceived digital transformation climate

Abstract This study investigates how artificial intelligence tools improve perceived innovation capability within sports firms, focusing on the parallel mediating roles of workplace enjoyment and supportive climate, organizational identification, and AI-enhanced work engagement,...

Artificial intelligence adoption and green collaborative innovation: knowledge-based channels and governance conditions

Purpose This study aims to examine whether and how firm-level artificial intelligence (AI) adoption promotes green collaborative innovation. It focuses on two knowledge-based capability channels, namely, knowledge learning capability and green governance capability, and investiga...

Nanoplastics Mitigate 6PPD-Induced Zebrafish Cardiac Ferroptosis Mediated by the GRK5/p53/SLC7A11 Pathway

Abstract 6PPD, as an antioxidant in tire rubber, constitutes an emerging pollutant together with nanoplastics (NPs) widely present in the environment. This study explored the potential combined toxicity risk of 6PPD and 50 nm polystyrene nanoplastics (PS-NPs) to aquatic ecosystem...

Life-stage-resolved toxicological assessment and environmental relevance of triclosan in the freshwater gastropod Biomphalaria glabrata

TCS (triclosan) is frequently detected in freshwater compartments, including surface water, sediments, biosolids, and pore water; however, its life-stage-specific toxicity in gastropod mollusks remains insufficiently characterized. To address this gap, this study aimed to determi...

Stem cell–based approaches in hepatitis B virus–related liver disease: therapeutic potential and advances in human-derived research models

Persistent hepatitis B virus (HBV) infection is a major cause of chronic hepatitis, liver fibrosis, cirrhosis, HBV-related acute-on-chronic liver failure (ACLF), and hepatocellular carcinoma. Although nucleos(t)ide analogues and pegylated interferon alfa suppress viral replicatio...

The relationship between biological rhythm disturbances and mixed features in major depressive episodes: a multicenter cross-sectional study

Major depressive episodes (MDEs) with mixed features are associated with greater clinical complexity and may represent an important indicator of bipolarity. Biological rhythm disturbances have been implicated in mood disorders, but their relationship with mixed features during MD...

High immunosuppressants variability adversely affects post-transplant recurrence for patients with hepatocellular carcinoma

Tumor recurrence after liver transplantation (LT) for hepatocellular carcinoma (HCC) is the most significant obstacle impacting the prognosis of patients. Managing the clinical application of immunosuppressive agents is difficult, owing to their limited therapeutic range and nota...

Tail convergence in insurance financial protection: multi-layer performance among hospitalised NCD patients in Southwest China

Introduction China’s multi-layer health insurance system provides financial protection through basic insurance (Urban Employee Basic Medical Insurance [UEBMI] and Urban-Rural Resident Basic Medical Insurance [URRBMI]), catastrophic supplemental coverage, and medical assistance. U...

Automatic sleep stage classification via non-contact BCG and dual-layer modeling

Abstract Traditional sleep staging studies often rely on contact sensors, which may interfere with natural sleep. Therefore, this study proposes an automatic sleep staging method based on non-contact single channel ballistocardiogram (BCG) signals. Firstly, discrete wavelet trans...

Itaconate as a central node in immunometabolism and inflammatory control

Mitochondria serve as central regulators of cellular bioenergetics and inflammatory signaling, integrating metabolic status with immune responses. Disruption of mitochondrial homeostasis, including altered tricarboxylic acid cycle dynamics, redox imbalance, and aberrant reactive...

Gut Microbiota and Metabolites: Orchestrating Depression Pathogenesis Through the Microbiota–Gut–Brain Axis’s Neural, Immune, and Metabolic Routes

Depression (major depressive disorder, MDD) is a globally prevalent, highly disabling, and complex mental disorder whose pathogenesis has not been fully elucidated. In recent years, the role of the gut microbiota in depression via the “microbiota–gut–brain axis” (MGB axis) has at...

Experimental investigation of magnesium phosphate cement mortar for the repair of long-term marine-exposed concrete

Chloride ions tend to ingress rapidly in damaged areas of marine concrete structures, such as cracks and spalling zones. Without timely intervention, embedded steel reinforcement in these regions undergoes accelerated corrosion, ultimately compromising structural integrity. To re...

Characteristics and consultation patterns of patients using telemedicine for peritoneal dialysis: a retrospective observational study

This study aimed to characterize patients receiving peritoneal dialysis (PD) who used Internet hospital specialist nursing consultations and to explore their consultation patterns. Findings are intended to inform telemedicine policy refinement and improve understanding of service...

The intratumoral microbiome as an emerging hub in cancer pathogenesis and precision oncology

Over the past decade, the number of microbial communities identified within tumors has increased by 400%. Notably, the intratumoral microbiome, which includes bacteria, fungi, viruses, and other microorganisms within tumor tissues, was first discovered more than a century ago. Ba...

Design, synthesis, crystal structure, fungicidal activity and in silico study of novel pyrazole carboxamide derivatives containing flexible chain

Pyrazole-containing compounds are significant in agrochemical discovery due to their diverse biological activities. Inspired by commercial succinate dehydrogenase inhibitor (SDHI) fungicides featuring flexible linkers, a series of novel pyrazole-carboxamide derivatives containing...

Pseudocapacitive Charge‐Driven Adhesive‐Electrocoupling Hydrogels for Myocardial Infarction Repair via Interstitial Microenvironment Remodeling

ABSTRACT Myocardial infarction (MI) creates a hostile microenvironment characterized by oxidative stress, inflammation, fibrosis, and electrical conduction block, posing a multifaceted challenge for tissue repair. To address this, we developed a multifunctional hydrogel (Gel‐PDZC...

Comparison between the blood urea nitrogen (BUN)-to-creatinine ratio and four urinary biomarkers of dehydration; a cross-sectional study in fasting patients awaiting surgery

The blood urea nitrogen (BUN)-to-plasma creatinine ratio is a conventional method for diagnosing dehydration. We examined the relationship between this method and the more recently promoted urine biomarkers of dehydration. Blood and urine sampling was performed in 921 patients wh...

Synergy Between Air Pollution and Carbon Emissions of On-Road Mobile Sources, Evidence from a Typical Southwestern Region in China

The transport sector has emerged as a significant source of greenhouse gases and airborne pollutants. However, few studies have carried out a comprehensive assessment of the synergistic benefits between air pollutant and carbon emission reductions that account for the unique regi...