Yunnan Agricultural University

Crop Growth Models: Development, Applications, Recent Advances, and Future Perspectives

Global climate change has posed a serious threat to agricultural production and food security. Crop growth models, with their excellent simulation and prediction capabilities, have become one of the important tools for guiding agricultural production and ensuring food security. T...

Biostimulatory Effect of 3-Acetonyl-3-Hydroxyoxindole on the Growth and Secondary Metabolites of Khaya senegalensis: UPLC–MS/MS Profiling and Molecular Docking Insights

Developing sustainable agricultural biostimulants that simultaneously optimize vegetative growth and specialized metabolic pathways is critical for maximizing plant growth, photosynthetic efficiency, and metabolome reprogramming. In this study, for the first time, the effects of...

In Vitro and Embryonic Evaluation of Recombinant Larus ridibundus IFN-α and Mx Proteins Against Newcastle Disease Virus

Newcastle disease virus (NDV) is an important avian pathogen that can circulate in migratory birds, including Larus ridibundus. This study examined the transcriptional responses and anti-NDV activities associated with recombinant IFN-α and Mx proteins from L. ridibundus. The IFN-...

Molecular Epidemiological Characteristics and Genetic Evolution of Bluetongue Virus in Yunnan Province, China

Bluetongue is an insect-borne disease of ruminants caused by the Bluetongue virus (BTV). It is primarily transmitted through the bites of Culicoides midges and is widely distributed in tropical, subtropical, and temperate regions around the world. Due to its favorable geographica...

MicroRNA expression profiling in fowl adenovirus serotype 4-infected Leghorn male hepatoma cells using small RNA deep sequencing

Fowl adenovirus serotype 4 ( FAdV-4 ) is the causative agent of hydropericardium-hepatitis syndrome ( HHS ), a disease that causes severe economic losses to the global poultry industry. MicroRNAs ( miRNAs ) are key regulators of host–pathogen interactions; yet, their temporal exp...

Structure-based design of peptide inhibitors targeting the SPSB2–iNOS interaction: a computational approach to modulating nitric oxide signaling

Dysregulation of inducible nitric oxide synthase (iNOS) plays a central role in inflammatory diseases, cancer, and neurodegeneration due to excessive nitric oxide (NO) production. Suppressor of Cytokine Signaling Box Protein 2 (SPSB2) is a key negative regulator of iNOS through s...