Xavier University of Louisiana

The Art of Misunderstanding Special Relativity: A Case Study of Jan Slowak

In his paper “Lorentz Transformations, Time Dilation & Reality”, Slowak performs what he calls a “logical analysis” of the Lorentz transformation and the time-dilation formula. He claims that these do not agree with “reality”, a claim that flies in the face of over 120 years of s...

Development of a STEAP1-targeted prostate cancer specific antibody drug conjugate platform with immunostimulatory properties

Background: Patients with prostate cancer who develop androgen pathway modulation resistant (APMR) disease face lethal outcomes despite advances in androgen receptor-pathway inhibitors, chemotherapy, and PSMA-directed radioligands. Antibody-drug conjugates (ADCs) have demonstrate...

CK2 targeting potentiates antineoplastic effects of dual HER2/EGFR inhibitor lapatinib and attenuates growth factor-induced epithelial-mesenchymal transition

CK2 is a pleiotropic, heterotetrameric kinase elevated in numerous cancers and, as such, has garnered much attention as a target for novel antineoplastic agents. Currently, silmitasertib, a selective CK2 inhibitor, has an orphan designation for medulloblastoma and neuroblastoma....