Wroclaw Medical University

Intraoperative Techniques Aiding Margin Assessment and Nerve Sparing During Robot-Assisted Radical Prostatectomy

Robot-assisted radical prostatectomy (RARP) requires a balance between complete cancer excision and preservation of urinary continence and erectile function. Because the preservation of neurovascular bundles adjacent to the prostate surface contributes to postoperative functional...

Morphology of third mandibular molars – an in vivo cone beam computed tomography study in Lower Silesia

<title>Abstract</title> Background Understanding the root and canal morphology of mandibular third molars (MTMs) is crucial for anatomical characterization of human dentition and effective endodontic treatment. This study investigates the number of roots, canal configurations, an...

Effects of Additive Incorporation on Fluoride Release of Orthodontic Glass Ionomer Cements and Adhesives: A Systematic Review

This systematic review evaluated the effects of functional additives on fluoride release, fluoride recharge/re-release, and selected mechanical, physical, and biological properties of orthodontic glass ionomer cements (GICs) and glass ionomer-based adhesives. The review followed...

Illness Acceptance Among Adults with Melanoma: A Prospective Observational Cross-Sectional Study

Introduction: Melanoma is a chronic disease that significantly affects patients’ daily functioning and emotional well-being. Beyond its somatic burden, it often leads to substantial changes in quality of life (QoL). This study aimed to assess illness acceptance among melanoma pat...

Context Dependent Effects of Probiotics: A Systems Perspective on the Interpretation of Experimental Findings

Current definitions of probiotics emphasize their beneficial effects on the host but do not fully capture the complexity of their interactions within the host. Most experimental models remain reductionist, focusing on individual probiotic strains rather than the biological system...

Towards Personalized Medicine in Chronic Kidney Disease: A Roadmap for the future of Early Detection, Diagnosis, and Management: A Consensus Roadmap from the EUTox, PerMedik and KidneyHealth networks

Chronic kidney disease (CKD) affects more than 800 million individuals worldwide and represents one of the fastest‑growing causes of morbidity and mortality. Despite major therapeutic advances, CKD is frequently detected only after substantial and irreversible loss of kidney func...

Diagnostic and therapeutic significance of selected antibodies against advanced glycation end-products (anti-AGEs)

The aim of this review is to summarize current knowledge on the diagnostic and therapeutic significance of antibodies against advanced glycation end-products (anti-AGEs). AGEs are formed through non-enzymatic reactions of reducing sugars with proteins, lipids, and nucleic acids,...