Wellesley College

Long-read low-pass sequencing detects a validated structural variant in the equine myostatin (MSTN) gene

Abstract Objectives Low-pass sequencing trades read depth for throughput, an established strategy for genotyping with short-read sequencing. Whether this tolerance extends to structural variant (SV) detection at the level of a single, biologically validated locus has been compara...

Spread and Sustainability of an Antimicrobial Stewardship Initiative Within a Pediatric Network

BACKGROUND: Projects employing performance feedback with education have been used to improve antimicrobial prescribing practices, but improvements may not be sustainable after the active intervention. We sought to determine whether ongoing clinical decision support (CDS) could su...

Molecular Evaluation of Deep Eutectic Solvents for Wet Algae Lipid Extraction and Biofuel Production

Abstract Microalgae represent promising feedstocks for biofuel production, yet cell-wall disruption remains a critical bottleneck for scaling up lipid extraction. This study evaluates four cholinium-based ionic liquids (ILs) and deep eutectic solvents (DESs) as green, energy-effi...

Perceptual evidence for a gestural representation of aspiration

Is aspiration part of the preceding consonant, part of the following vowel, or both? It behaves in many ways like part of the consonant which it is marked as occurring on, but it also contributes to listeners' perception of vowel duration. Previous work shows that vowels are perc...

Comparative Effectiveness of Continuous Glucose Monitoring Versus Blood Glucose Monitoring in Pregnancy With Diabetes: Systematic Review and Meta-analysis With Trial Sequential Analysis

OBJECTIVE The value of adding continuous glucose monitoring (CGM) to blood glucose monitoring (BGM) during pregnancy is unclear. PURPOSE To clarify CGM's role in pregnancy using meta-analysis, Grading of Recommendations Assessment, Development and Evaluation (GRADE) ratings, harm...

Crystallizationfor Manufacturing in Microgravity;Are We There Yet?

Abstract Crystallization in microgravity has been extensively investigated because of its potential to enhance crystal quality compared to terrestrial conditions. While early efforts were primarily directed toward single-crystal growth for structural studies, increasing attention...