University of Zambia

A systematic review of advances and challenges in stroke prevention in sickle cell disease since the STOP trials

Abstract Background Stroke is among the most disabling complications of sickle cell disease (SCD). The STOP trials established transcranial Doppler (TCD) screening with chronic transfusion as the basis of primary stroke prevention. Implementation remains uneven, however, and evid...

Protocol for a cluster randomized controlled trial among young people and their peers to reduce substance use and inequitable gender beliefs in Southern Africa

BACKGROUND AND AIMS: Substance use and the internalization of traditional gender norms, or inequitable gender beliefs, are co-occurring risk behaviors for poorer health and well-being in young people in Southern Africa. Addressing the social and structural factors that reinforce...

Africa’s first standard measure for child and adolescent health: The Nigerian EQ-5D-Y-3L value set using composite time trade-off and discrete choice experiments

Nigeria has a rapidly growing child and adolescent population, yet no locally derived EQ-5D-Y-3 L utility weights (value set) exists for estimating quality-adjusted life years (QALYs) in paediatric economic evaluations. This study developed the first Nigerian EQ-5D-Y-3 L value se...

Diversity and distribution of ticks collected from vegetation and domestic animals in Zambia

Ticks are major vectors of pathogens affecting livestock and human health in sub-Saharan Africa, yet integrated data on tick diversity across ecological gradients remain limited. In Zambia, most studies have focused on livestock-associated ticks, with little emphasis on compariso...

Emergency obstetric and newborn care availability, utilization and referral capabilities in Zambia using a national facility census

Abstract Introduction Improving maternal and newborn health remains a global priority. Despite an increase in the number of health facilities providing childbirth services, not all can perform basic or comprehensive emergency obstetric and newborn care (EmONC) to avert maternal a...

Prevalence and factors associated with depression and/or anxiety among adults in Zambia using the 2024 Zambia demographic and health survey: a multilevel analysis

Depression and anxiety are leading causes of disability globally, yet national epidemiological evidence from Zambia remains scarce. This study estimated the prevalence of depression and/or anxiety among Zambian adults, identified individual and community-level factors associated...

A modified Delphi study of expert consensus on mental health service access and digital strategies for adolescents and young people living with HIV in Zambia

Adolescents and young people living with human immunodeficiency virus (HIV), hereafter AYPLHIV, experience depression, anxiety, behavioural difficulties, and psychosocial distress that may undermine antiretroviral therapy (ART) adherence and long-term HIV outcomes. In Zambia, men...

Behavioural capability in leadership development: from individual enactment to collective consequence

Purpose The purpose of this paper is to examine a recurring but underdeveloped issue in leadership development scholarship: the tendency to assume that leaders who understand effective leadership behaviour will also be able to enact it in practice. It argues that this assumption...

Household catastrophic out-of-pocket expenditure and the socioeconomic burden of paediatric surgery: a cross-sectional study at the highest tertiary hospital in Zambia

Globally, about 81 million people per year are driven to financial catastrophe from the costs of surgery and other related nonmedical costs, with low- and middle-income countries (LMICs) bearing the greatest burden. This study determined the catastrophic out-of-pocket (OOP) healt...

Pharmacological pain relief and postpartum bleeding in women with moderate or severe anemia: A cohort analysis of the WOMAN ‐2 trial

OBJECTIVE: Pain relief could minimize blood loss by limiting the adrenaline stress response to fear and trauma during birth. We examined the association between pharmacological pain relief and postpartum bleeding in a large cohort of women giving birth with anemia in sub-Saharan...

Incidence and risks of adverse fetal and neonatal outcomes in the LABOR study, a prospective intrapartum cohort in four tertiary referral centers in Ghana, India, and Zambia

Abstract Background Globally, more than two million perinatal deaths occur annually attributable to the intrapartum period, the vast majority occurring in low- and middle-income countries (LMICs). We sought to ascertain the incidence of adverse neonatal intrapartum-related outcom...

Factors associated with retakes in health professions courses: a case study of five selected universities in Sub-Saharan Africa

Abstract Background Academic examination retakes are significant challenges in health professions education. With rigorous clinical assessments, limited training resources and high-stakes examinations, students struggle to meet academic requirements which cab result in retakes. T...

How Norms Depend on the Presence and Status of Observers: The Relational Contingency of Everyday Behaviors in 90 Societies

Norms are fundamental to social life, but basic questions about how they are affected by social context remain. Specifically, how do normative constraints depend on the presence and status of observers, and how do such relational contingencies vary across cultures? Using data fro...

EXAMINING INVENTORY VALUATION MANAGEMENT AND CONTROL IN MANUFACTURING FIRMS: A CASE STUDY OF COCA-COLA COMPANY IN NDOLA DISTRICT, ZAMBIA

The need for holding inventories is invented in any business organisation. The space of inventory will be properly controlled so that the object of carrying or maintaining adequate inventory lauds at minimum cost can be realised. This research is aimed at finding out the effect o...

EXAMINING INVENTORY VALUATION MANAGEMENT AND CONTROL IN MANUFACTURING FIRMS: A CASE STUDY OF COCA-COLA COMPANY IN NDOLA DISTRICT, ZAMBIA

The need for holding inventories is invented in any business organisation. The space of inventory will be properly controlled so that the object of carrying or maintaining adequate inventory lauds at minimum cost can be realised. This research is aimed at finding out the effect o...

Knowledge, attitude, and practice of antifungal resistance and stewardship among pharmacy students in Zambia: a cross-sectional study to inform antifungal stewardship programs

Background Antifungal resistance (AFR) is a growing global health threat, particularly in low- and middle-income countries such as Zambia, where antifungals are often accessed without prescription. Antifungal stewardship (AFS) programs aim to optimise antifungal use, yet limited...

One in seven has severe pain: a point-prevalence study of hospitalised patients across Africa

ABSTRACT: Acute pain in hospitalised patients is common, yet African data are scarce. We conducted a prospective point-prevalence study of hospitalised adult patients across Africa to determine acute pain prevalence and severity and investigate associations of pain with critical...

Monitoring and Human Health Assessment of Trace Elements in Fresh and Dry Fish From Lake Kariba, Siavonga, Zambia

This study investigated the levels of trace elements in two fish species, Kariba bream (Oreochromis mortimeri) and Kapenta (Limnothrissa miodon) from Lake Kariba in two consecutive years, 2021 and 2022. Both Kariba Bream fresh/sun-dried muscle and sun-dried Kapenta tissues were d...