Institution
University of Wisconsin System
Recent research
- Engineering & TechnologyOpen access
Tunable Polariton Canalization in Natural Van Der Waals Oxide
ABSTRACT Hyperbolic phonon polaritons (HPPs) are coupled oscillations of anisotropic lattice vibrations and electromagnetic fields that confine the latter to the nanoscale, enabling novel nano‐polaritonic devices. While HPPs have been identified in multiple layered materials, ach...
- Physics & SpaceOpen access
Abstract We construct and characterise a sample of 146 little red dots (LRDs) across 2.0 < z < 9.3, selecting all sources with v-shaped UV-optical continua from JWST NIRSpec/PRISM spectra and compact morphologies in NIRCam/F444W imaging. We show that LRD continuum spectra are wel...
- BiologyOpen access
After administering genome editors, their efficiency is limited by a multi-step process involving cellular uptake, trafficking, and nuclear import of the vector and its payload. These processes vary widely across cell types and differ depending on the nature and structure of the...
- Biology
Phenotypic plasticity can influence population persistence, range dynamics, and evolutionary potential in heterogeneous landscapes. If adaptive, plasticity may buffer populations against environmental variability, climate change, and extreme events. Yet, few studies have examined...
- BiologyOpen access
Isolation of Phytoecdysteroids:Ajugasterone C and20-Hydroxyecdysone, from Sida alba Linn.
Abstract Medicinal plants are employed in folk medicine as enormous reservoirs of secondary metabolites, with varied and distinctive chemical and biological properties, that can prevent, treat, or cure diseases. Consequently, the validation of traditional remedies has remained a...
- BiologyOpen access
Patients with vitiligo reportedly have an increased risk of sensorineural hearing loss (SNHL), driven by the loss of extracutaneous melanocytes in the inner ear. In a phase 2 dose-ranging study, the oral, selective Janus kinase 1 inhibitor povorcitinib demonstrated substantial re...
- BiologyOpen access
A multi-ancestry polygenic risk score for body mass index predicts longitudinal weight change
Abstract Background Identifying individuals at risk for future weight gain is challenging, partly because associations with traditional clinical risk factors may be biased by confounding and reverse causation. Polygenic risk scores (PRS) provide a stable, lifelong measure of gene...
- Biology
Structure-Based Insights into the Molecular Mechanisms of LuxR-Type Quorum Sensing Receptors
Quorum sensing (QS) enables bacteria to coordinate collective behaviors in response to population density. LuxI/R QS systems, common among gram-negative bacteria, consist of a LuxI-type synthase that produces an N- acyl L -homoserine lactone (AHL) signaling molecule and a LuxR-ty...