University of Vienna

GH172 Difructose Dianhydride I Synthase: A Two‐Stepped Journey via Glycosylation and Cyclization Using QM/MM Metadynamics

ABSTRACT The difructose dianhydride I synthase/hydrolase catalyzes the reversible transformation of inulobiose into difructose dianhydride I, a component of caramel. The proposed reaction mechanism of such a transformation consists of a glycosylation step followed by a cyclizatio...

Loss of Twist impairs tentacle development and induces epithelial neoplasia in the sea anemone Nematostella vectensis.

Appendages are key features of the body plans of arthropods and vertebrates, yet little is known about appendage formation outside of bilaterians. Here, we investigate the molecular regulation underlying the formation of tentacles, the appendages in cnidarians. We find that the b...

Experimental constraints on the differentiation of CM-like planetary embryos

This study investigates the onset of differentiation of hydrous (ice-bearing) planetary embryos in the early Solar System. To do so, we conducted high-pressure (1 GPa) melting experiments on a CM2 chondrite (MCY12002) across a temperature range of 1050-1400°C, with durations vary...

Learning German Language & Culture

We start studying german language & culture. The Carreer opportunities are great.

The impact of stochastic sea ice perturbations on seasonal forecasts

Abstract. Sea ice ensemble forecasts can be highly underdispersive, meaning that the ensemble spread is notably lower than the average forecast error. One common strategy to address underdispersion is to add stochastic perturbations to the forecasts. We detail the implementation...

Un/making protection: EU temporary protection and the governance of the Ukrainian displaced in Vienna in a global perspective

This article explores the reception of the Ukrainian displaced in Vienna following Russia’s full-scale invasion in 2022, and the workings of temporary protection (TP). It analyses how response to the mass influx of displaced persons has been shaped jointly by the legacies of mana...

An evolutionarily conserved N-terminal domain of RRF-3 governs GTSF-1 binding in nematodes

Abstract GTSF1 is an essential activating cofactor for PIWI proteins in many metazoans. In the nematode Caenorhabditis elegans , however, GTSF-1 does not bind PIWI, but is associated with the RNA-dependent RNA polymerase RRF-3, supporting endo-siRNA (26G-RNA) biogenesis. Here, we...

The Art of Printing [3D Engineering & Advanced Geometry]

There are sequences of actions that we repeat everyday. Among them is the printing action: print a numeric paper in pdf format and save it on your computer, or print it using a Xerox Machine or HP-printer. We found out we can do More: Let us Print in 3D Dimension, and investigate...

Placebo Analgesia Does Not Generalize From Pain to Interoceptive Abilities: A Preregistered Exploratory Study

Placebo pills reliably reduce pain. Pain perception is tied to increased arousal and heart rate. Heart rate perception is, in turn, closely related to interoceptive signals processing, for example, pain and autonomic regulation. However, no studies so far have systematically exam...

Pragmatic Variation in Greeting and Farewell Formulae in Rural Austria

Greeting and farewell formulae are highly conventionalized routines that index social relations, regional norms and situational formality. This paper investigates pragmatic variation in greetings and farewells in rural Austria, focusing on age, region, setting and prosodic design...

Lorentzian Gromov–Hausdorff convergence and pre-compactness

Abstract The goal of this paper is to introduce a notion of convergence à la Gromov–Hausdorff for Lorentzian spaces, based on 𝜀-nets formed by causal diamonds and depending solely on the time-separation function. This provides a geometric framework for convergence that applies bo...

Transposon end recognition and excision mechanisms of type I-F CRISPR-associated transposases

Abstract CRISPR-associated transposons (CASTs) are Tn7-like elements that have co-opted RNA-guided CRISPR effectors for targeted DNA insertion. CASTs have been adapted as genome editing tools for programmable, site-specific integration. Among them, the type I-F system from Ps e u...

The benefit of neighborhood methods for the assimilation of cloud‐affected radiances evaluated in observing‐system simulation experiments

Abstract Deficiencies in the representation of hydrometeors and subgrid‐scale motions in numerical weather prediction models cause systematic differences between satellite observations and their model equivalents, which pose a significant challenge for the assimilation of cloud‐a...

The role of chloride ions in serotonin transport

Abstract The human serotonin (5-HT + ) transporter SERT facilitates 5-HT + transport into cells by coupling it to Na + symport and K + antiport. Although extracellular Cl − is also essential for transport, Cl − co-transport has been disputed, raising questions about the role of C...

How transgender, gender diverse (TGD) and cisgender youth cope with daily stress: Insights from an Ecological Momentary Assessment Study

This study investigated gender minority stress (GMS), coping, and mental health in trans, gender diverse (TGD) and cis youth in Germany and Austria and explored immediate effects of coping on stress in daily life. A 14-day Ecological Momentary Assessment (EMA) study containing th...

Hidden diversity and complex transmission networks of Taeniidae and Dipylidiidae tapeworms in the Western Balkans revealed by mitochondrial markers

Abstract Background Cestodes of the families Taeniidae and Dipylidiidae constitute a neglected but epidemiologically important group of parasites, including species of veterinary and zoonotic relevance. In the Western Balkans, their molecular epidemiology, host range, and transmi...

Multisoliton Solutions and Blow Up for the $$L^2$$-Critical Hartree Equation

Abstract We construct multisoliton solutions for the $$L^2$$ L 2 -critical Hartree equation with trajectories asymptotically obeying a many-body law for an inverse square potential. More precisely, we consider the m -body hyperbolic and parabolic non-trapped dynamics. The pseudo-...

Rothe Time Discretization and Weak Solutions for a Cutoff Westervelt System

ABSTRACT We study a fully implicit Rothe time discretization for a cutoff first‐order formulation of the Westervelt equation. The key ingredients are the enthalpy variable and the primitive mobility variable, which turn each nonlinear time step into a uniformly monotone elliptic...

Spatial heterogeneity in post-fire permafrost evolution as revealed by satellite radar observations

Abstract. Wildfires, which have profound impacts on permafrost environments, are expected to increase in frequency and intensity as a result of climate change. This study aims to enhance our understanding of how wildfires affect permafrost by investigating multiple Arctic tundra...

Enhanced Line Search Improves Robustness and Efficiency of Pose Sampling in Protein–Ligand Docking

Abstract Physics-based protein–ligand docking critically depends on efficient pose sampling, yet established sampling and local refinement algorithms can be inefficient and unstable in the highly nonconvex energy landscapes characteristic of protein–ligand interactions. To addres...