University of Verona

The future of high-dose, high-intensity neurorehabilitation: Consensus-based core recommendations from the fourth Stroke Recovery and Rehabilitation Roundtable

Objective: Convergent evidence indicates that high-dose, high-intensity rehabilitation (HDHI) improves outcomes beyond usual care after stroke, yet implementation remains limited. While questions of optimal dose, timing, and delivery format continue to be refined, the biological...

Pancreatic ductal adenocarcinoma and its subtypes: clinical relevance of histopathology and molecular characterization, integrating the key updates of the 2026 WHO classification

Abstract Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal human cancers, due to its late clinical presentation, early vascular, perineural, nodal and distant dissemination, and profound resistance to systemic therapies. Histologically, conventional PDAC is charac...

Cross-Currency Heath–Jarrow–Morton Framework in the Multiple-Curve Setting

Abstract. We provide a general Heath–Jarrow–Morton (HJM) framework for forward contracts written on abstract market indices with arbitrary fixing and payment adjustments and featuring collateralization in any currency denomination. In view of this, we first provide a thorough stu...

Continuous Glucose Monitoring and Automated Insulin Delivery in Infants with Type 1 Diabetes: Real-World Evidence to Support Future International Guidelines

To evaluate efficacy and safety of continuous glucose monitoring (CGM) and automated insulin delivery (AID) in infants. A retrospective multicenter study (13 centers) of 76 children diagnosed with antibody-positive type 1 diabetes before age 2. Outcomes at 12 months were compared...

Retrohepatic Vena Cava Encirclement, as Surrogate of Extensive Liver Manipulation During Caval Sparing Hepatectomy, Is a Risk Factor for Tumor Recurrence After Liver Transplantation for Hepatocellular Carcinoma

ABSTRACT Introduction In liver transplantation (LT) with a caval sparing (CS) approach, the presence of complete encirclement of inferior vena cava (IVC‐E) by hypertrophic segment 1 increases the technical complexity of hepatectomy. Thus, in LT for hepatocellular carcinoma (HCC),...

Triple potentiator combinations increase the functional correction of several CFTR gating mutants

The Trikafta drug combination, comprising the corrector tezacaftor (VX-661), the potentiator ivacaftor (VX-770) and the dual corrector/potentiator elexacaftor (VX-445), has been FDA-approved for treatment of cystic fibrosis caused by ~300 cystic fibrosis transmembrane conductance...

Robot-Assisted Versus Open and Laparoscopic Radical Nephrectomy with Inferior Vena Cava Thrombectomy forRenal Cell Carcinoma: A Systematic Review and Meta-Analysis

Background/Objectives: To compare perioperative, pathological, functional, and oncological outcomes of robot-assisted radical nephrectomy with inferior vena cava tumor thrombectomy (RARN-TT) versus open (ORN-TT) and laparoscopic (LRN-TT) approaches. Methods: PubMed, Scopus, and W...

Russian as a heritage language at university: contexts, experiences, motivations - Questionnaire (English translation)

This document contains the English translation of the questionnaire “Russian as a Heritage Language at University: Contexts, Experiences, Motivations,” originally administered in Italian as part of a study on Russian heritage language learners in Italian higher education. The que...

SIOOT® Adjunct Oxygen-Ozone Therapy Against Multidrug-Resistant Bacteria: A Pilot Study of 257 Cases

Background/Objectives: Antimicrobial resistance (AMR) represents one of the greatest challenges to modern medicine, particularly in chronic infections sustained by multidrug-resistant (MDR) pathogens and biofilm formation. SIOOT® Oxygen–ozone major autohemotherapy (SIOOT®-O2-O3-M...

Adjunctive Antimicrobial Photodynamic Therapy in Non-Surgical Periodontal Treatment: Clinical and Microbiological Insights from a Randomized Split-Mouth Trial

Background/Objectives: Antimicrobial photodynamic therapy (aPDT) has been proposed as an adjunct to non-surgical periodontal therapy, although its benefits remain debated. This study evaluated the clinical and microbiological effects of aPDT combined with ultrasonic scaling and r...

The Extended Kalman Filter for constraint enforcement in the forward dynamics of multibody systems

<title>Abstract</title> The forward dynamics of multibody systems is widely exploited in engineering applications to simulate the behavior of complex mechanical systems undergoing kinematic constraints. It relies on the integration of the equations of motion of the system. Howeve...

A compendium of next-generation patient-derived models for diverse cancers

Abstract The development of new therapeutics and the validation of pathogenetic cancer mechanisms require representative laboratory models 1,2 . However, existing collections represent only a fraction of the diversity observed in human cancer 2–4 . Recent technologies have enable...

LC–MS/MS Determination of Hair GHB: Is Segmental Analysis Useful for Exogenous Discrimination?

Discrimination between endogenous and exogenous Gamma-hydroxybutyrate (GHB) in hair matrix is a major challenge in the forensic context. According to the UNODC, to verify a possible intake, GHB concentration should be compared with the subject's basal level. Most published studie...

Is Visual Vertical Perception Altered in Children and Adolescents with Spinal Misalignment? A Cross-Sectional Study

Background/Objectives. Spinal misalignment in childhood and adolescence may be associated with altered sensory integration and body representation. The subjective visual vertical reflects visual, vestibular, and somatosensory integration, but its relationship with pediatric spina...

DTT-based biofilm and conventional intraoperative cultures for the detection of prosthetic joint infections: a comparative study

BACKGROUND: Accurate diagnosis of prosthetic joint infection (PJI) remains challenging. Biofilm culture by sonication has been included according to EBJIS criteria; however, this method is associated with technical difficulties. Dithiothreitol pretreatment (DTT-P) biofilm culture...

Impact of climate-smart agriculture adoption on household food consumption expenditure in Ethiopia

Climate change poses significant challenges to the agricultural production system and food security. In response, the adoption of climate‑smart agriculture is imperative for strengthening climate resilience while improving farm productivity and food security. This study aimed to...

High-accuracy lung region segmentation and injury classification using deep networks

This study developed and evaluated a hybrid deep learning framework for automated lung segmentation and multi-class severity classification in chest CT scans, addressing key methodological gaps including heterogeneous dataset labeling, pseudo-label bias in segmentation, limited i...

Prognostic significance of ACADL and MCM2 in meningiomas: Current evidence and clinical implications.

-wildtype, hypermetabolic, and proliferative. The latter two groups have the worst clinical outcomes and are enriched in ACADL and MCM2 expression, suggesting their potential as immunohistochemical surrogates. The revision of the current literature on the expression of these mark...

The Motor Competence of Learning with a Perception-Awareness Approach: A Pilot Study in the Formal Learning Environment

Background/Objectives: Physical activity in primary school is increasingly recognized not only for developing skill-related fitness, but also for promoting well-being, motivation, and awareness of individual abilities. However, studies integrating quantitative performance data wi...