University of Trieste

Cold Quantum Gravimeters: An Introduction for Geophysicists

Abstract This paper aims at providing an accessible introduction to cold quantum gravimeters tailored for geophysicists. We do not focus here on geophysical applications, as these are already well known to geophysicists, but rather provide a pedagogical exposition of the quantum-...

Phosphorylated HPV‑16 E7 disrupts planar cell polarity in cervical cancer cells through vangl1 dysregulation

High‑risk (HR) human papillomaviruses (HPVs) rely on the continuous expression of the E6 and E7 oncoproteins to reshape epithelial biology, drive and sustain malignant transformation. The high‑risk E7 oncoprotein is multifunctional, and its phosphorylation by Casein Kinase II (CK...

The Behavior of the External Limiting Membrane and Ellipsoid Zone in Diabetic Macular Edema: A Population AI-Assisted Optical Coherence Tomography Study

Purpose: To investigate the behavior of the external limiting membrane (ELM) and ellipsoid zone (EZ) in diabetic macular edema (DME) using artificial intelligence (AI)-based optical coherence tomography (OCT) quantification. Methods: This was a cross-sectional study. OCT scans of...

Perceptual misalignment of texture representations in convolutional neural networks

Mathematical modeling of visual textures traces back to Julesz's intuition that texture perception in humans is based on local correlations between image features. An influential approach for texture analysis and generation generalizes this notion to linear correlations between t...

Scalable Fitting Methods for Multivariate Gaussian Additive Models with Covariate-dependent Covariance Matrices

We propose efficient computational methods to fit multivariate Gaussian additive models, where the mean vector and the covariance matrix are allowed to vary with covariates, in an empirical Bayes framework. To guarantee the positive-definiteness of the covariance matrix, we model...

The added value of echocardiography in pulmonary arterial hypertension risk assessment an artificial intelligence machine learning–derived analysis of the ULTRA RIGHT VALUE registry

Abstract Aims The right ventricle (RV) is a major determinant of outcome in pulmonary arterial hypertension (PAH), but its assessment has not been completely incorporated in the risk of mortality scores. We therefore evaluated the added value of echocardiography of the RV to risk...

Systemic inflammatory profiles associated with early EEG abnormalities following ischemic stroke: a cohort study

Abstract Background Post-stroke inflammation (PSI) contributes to acute brain injury and may influence early electroencephalographic (EEG) abnormalities after ischemic stroke. Although systemic inflammatory biomarkers have prognostic value, their association with specific EEG pat...

Integration of multiple perspectives to understand the left ventricular pressure–volume relationship

For more than a century, the pressure–volume loop has offered a simple and elegant way to show how the heart pumps blood. In one picture, it summarizes how the heart fills, contracts, and ejects blood. However, this simplicity has a limitation: the loop treats the heart as if it...

An exceptionally large and repetitive genome in the cave-dwelling shrimp Troglocaris planinensis

Introduction: Genomic resources for subterranean crustaceans remain scarce, limiting investigation of the molecular basis of adaptation to light-deprived environments. Troglocaris planinensis is a stygobiont freshwater shrimp endemic to the Dinaric Karst that lacks nuclear genomi...

A bifurcation phenomenon for the critical Laplace and p-Laplace equation in the ball: part 2

Abstract In this paper we continue the discussion started in [12] concerning a bifurcation phenomenon for radial solutions of the following nonlinear eigenvalue problem: $$\begin{aligned} {\left\{ \begin{array}{ll} \Delta _p u(x) + \lambda {\mathcal {K}}(|x|) \,u(x) \, |u(x)|^{q-...

Forest-skein groups III: simplicity

An Ore forest-skein category provides three forest-skein groups equipped with a powerful diagrammatic calculus analogous to Richard Thompson’s groups F\subset T\subset V . We investigate when forest-skein groups have simple derived subgroups and establish two characterisations: a...

Measurement Invariance of the Brief State Rumination Inventory Across Administration Methods, National Samples, and Sex

State rumination is a temporary activation of repetitive, negative, self-focused thinking in response to specific situational triggers or mood states. We present the results of two studies that examined the psychometric properties and measurement invariance of the Italian version...

Optimization and Intra-Laboratory Validation of the Neuro-2a Assay for Tetrodotoxin Detection in Mussels

Tetrodotoxin (TTX) is a potent marine neurotoxin responsible for severe seafood poisoning in humans, characterized by neurological symptoms that may be fatal. Originally identified as a natural contaminant of pufferfish (Tetraodontidae family), over the last few years TTX and its...

Characterization of diseases in temporal comorbidity networks

Comorbidity networks, or disease-disease networks, represent relationships between diseases and can reveal non-random disease associations and multimorbidity structure. These patterns reflect shared pathophysiology, diagnostic pathways, and risk of adverse outcomes. Using large-s...

Steady Vortex Sheets in Presence of Surface Tension

Abstract In this paper, we construct a new class of uniformly rotating vortex sheets arising as perturbations of the circular configuration within the Kelvin–Helmholtz model for two incompressible fluids of equal density, with surface tension effects taken into account. Despite t...

Addressing the Limits of Emx2 Therapy of Glioblastoma Multiforme by Transgene Insulation and Epigenetic Pharmacological Intervention

Introduction/Objectives: Implicated in the regionalization of the anterior central nervous system (CNS) and the progression of pallial astrogliogenesis, the transcription factor gene EMX2 has been reported to be specifically silenced in several tumors, both non-neural and neural....

Salivary hormones and adipokines are associated with glycemic control and early renal and cardiometabolic markers in children and young adults with type 1 diabetes

Abstract Purpose Type 1 diabetes (T1D) is recognized as a complex metabolic condition associated with hormonal dysregulation and early complications. This study aimed to evaluate salivary metabolic hormones and adipokines in children and young adults with T1D, and to assess their...

Antiarrhythmic Drug Therapy in Cardiomyopathies: A Comparative Synthesis of Guidelines and Consensus Documents

Abstract Purpose of Review Antiarrhythmic drug therapy in cardiomyopathies remains challenging because arrhythmic risk, drug efficacy, and pro-arrhythmic vulnerability vary substantially across phenotypes. This review summarizes contemporary guideline and consensus recommendation...

Cloning and characterization of intermediate Homer1E of human skeletal muscle

Abstract HOMER proteins are scaffolding proteins critically involved in intracellular signaling, calcium homeostasis, receptor trafficking and synaptic plasticity. Three human HOMER genes ( HOMER1 , HOMER2 , HOMER3 ) are expressed in both neurons and skeletal muscle fibers. HOMER...

Transient Laser‐Induced Periodic Surface Structures Revealed by Time‐Resolved EUV Diffuse Scattering

ABSTRACT The formation of permanent laser‐induced periodic surface structures (LIPSS) on solid surfaces under impulsive laser irradiation above the damage threshold has been the subject of extensive research. Here, we report the formation of transient quasi‐periodic surface modul...