University of Tokyo Health Sciences

Bone age estimation from chest radiographs using deep neural networks: a proof-of-concept study

Bone age (BA) is the gold standard for skeletal maturity assessment but is not routinely incorporated into pediatric growth evaluation workflow because it requires dedicated hand radiographs and specialist interpretation. To develop an estimation model for BA from chest radiograp...

Early life sugar rationing and ageing related diseases, biological ageing and mortality

Early-life nutrition may influence lifelong ageing, yet human evidence is scarce. Using Britain’s postwar sugar rationing as a natural experiment, we examine its long-term effects in 64,809 United Kingdom Biobank participants. Exposure to sugar rationing during the first 1,000 da...