University of Tabuk

Smoking-related knowledge, attitudes, and beliefs regarding cardiovascular and respiratory harms among health sciences students who currently smoke in Saudi universities

Tobacco smoking is a major preventable cause of cardiovascular and respiratory morbidity worldwide. Although conventional cigarettes are strongly linked to serious chronic diseases, e-cigarettes generally result in lower toxicant exposure than conventional cigarettes but are not...

Combined Omeprazole and Glycyrrhiza glabra L. Extract Attenuate Ethanol-Induced Gastric Ulceration Through Modulation of TLR4/NF-κB/NLRP3 Signaling and Upregulation of PI3K/AKT/mTOR Gene Expression

Ethanol (EtOH)-induced gastric ulcer (GU) is a common model used to investigate mechanisms of mucosal injury and repair. Omeprazole (OMP) is a conventional anti-ulcer drug that effectively suppresses gastric acid secretion, but its efficacy may be enhanced by combining it with bi...

Combined Effects of Physiotherapy and Vitamin D Supplementation on Pain, Disability, and IL-6 Expression in Chronic Low Back Pain: A Randomized Controlled Trial

Background: Chronic low back pain (CLBP) is a leading cause of global disability, linked to elevated IL-6 and vitamin D deficiency or insufficiency. While interferential current (IFC) therapy and exercise therapy are established treatments, their combined effect with vitamin D su...

Policy Enablers for Renewable Energy Self-Consumption in Decentralised Energy Systems

Renewable energy self-consumption is increasingly relevant to Saudi Arabia not only as a sustainability measure under Saudi Vision 2030 but also as a mechanism that may support electricity system resilience, demand management, energy diversification, and investment. This study ex...

Safety and Efficacy of Colchicine for the Treatment of Pericarditis in Patients with Chronic Kidney Disease

This retrospective multicenter cohort study compared the safety and efficacy of low- versus high-dose colchicine in adult patients with chronic kidney disease (CKD) treated for pericarditis between August 2015 and August 2024. CKD was identified using ICD codes and confirmed by a...

Renal outcomes of SGLT2 inhibitors in ADPKD: a narrative review from mechanistic rationale to clinical trials

Abstract Inhibitors of the sodium-glucose cotransporter-2 (SGLT2i) were initially created for managing diabetes mellitus but have suggested significant renoprotective advantages regardless of blood glucose levels. SGLT2-inhibitors have thus emerged as a crucial component in the t...

Synthesis, modelling, biological activity of new thiophene hybridized with pyrazole, and/or pyridine analogues as potential DNA gyrase and topoisomerase IV inhibitors

Promoted by the well-established, valuable biological activity of thiophene-based hybrids, the study displayed the synthesis of two series of thiophene-pyrazole hybrids, 7a-c and thiophene-pyridine hybrids 9a-c, via reacting arylhydrazone with halogenated reagents and nucleophili...

Examining the distinctiveness of the Minnesota Living with Heart Failure Questionnaire from depressive symptoms in patients with heart failure

The Minnesota Living with Heart Failure Questionnaire (MLHFQ) is widely used to assess health-related quality of life (HRQOL) in patients with heart failure (HF), but conceptual overlap with depressive symptoms may complicate interpretation of patient-reported outcomes. To evalua...

Circulating inflammatory biomarkers and antifungal susceptibility in Candida albicans vulvovaginal candidiasis: a retrospective observational cohort study

Vulvovaginal candidiasis (VVC) affects millions of women worldwide. The rates of antifungal resistance are increasing, which can complicate therapy. Whether circulating inflammatory biomarkers reflect antifungal susceptibility patterns in localized VVC remains unclear. In this st...

Resolution of severe autoimmune hemolytic anemia and thrombocytopenia associated with Plasmodium vivax malaria without corticosteroid therapy: A case report

Rationale: Autoimmune hemolytic anemia is a rare but potentially life-threatening complication of Plasmodium vivax malaria. Most reported cases required corticosteroid therapy in addition to antimalarial treatment. Patient concerns: We report the case of a 28-year-old Ethiopian m...