University of South Florida

A rare right perirenal hemangioma mimicking a retroperitoneal “malignant lesion”: Diagnostic and procedural challenges of an extra-renal vascular mass

Perirenal hemangiomas are rare benign vascular tumors that can present as indeterminate retroperitoneal masses and mimic renal, adrenal, or soft-tissue malignancy. We report the case of a 60-year-old woman who was incidentally found to have a right perirenal mass adjacent to the...

Population genomics unravel structural variation of venom-encoding genes across the desert viper genus Cerastes

Understanding the molecular mechanisms underlying phenotypic differentiation is central to evolutionary biology. Yet most traits are shaped by complex, polygenic architectures, making links between genomic change and phenotype difficult to resolve. Venom provides an advantageous...

Mix&Fix-Net: A dual-stage trajectory prediction model for AIS and vision-derived vessel data

Vessel trajectory prediction is critical for maritime safety and accident prevention. While most existing trajectory prediction models rely on Automatic Identification System (AIS) data due to its precision and availability, small vessels mostly operate without AIS, resulting in...

Type 2-low Asthma: Epidemiology, Multiomics, and Emerging Therapies

Abstract Purpose of Review Type 2-low (T2-low) asthma, characterized by low blood and sputum eosinophils and low fractional exhaled nitric oxide (FeNO), remains a major unmet need because of frequent corticosteroid insensitivity and a lack of targeted therapies. This review summa...

Intratumor delivery of a novel plasmid combination induces high levels of metastatic melanoma regression

Direct intratumoral administration of immune-stimulating agents can generate systemic immunity following a tumor-localized immune response. Interleukin 12 (IL-12) activates T cells and reverses immunosuppression, generating a localized patient-antigen-specific immune response. Ch...

Relaxation approach to quantum-mechanical modeling of ferroelectric and antiferroelectric phase transitions

Ferroelectrics and antiferroelectrics are the electric counterparts of ferromagnets and antiferromagnets. These materials undergo temperature- and electric-field-induced phase transitions that give rise to their characteristic hysteresis loops. Modeling such hysteresis loops and...

Failure to invest below-ground may limit the northern expansion of invasive knotweed: lessons from a two-phase transplant experiment

Abstract The ecological and evolutionary processes determining species distributions and range limits remain poorly understood. Ultimately, range limits depend on the species’ abilities to persist under heterogeneous conditions, by adaptive differentiation and phenotypic plastici...

Early Palliative Care Is Feasible and Acceptable in Pediatric Neuro‐Oncology

BACKGROUND: Children with central nervous system (CNS) tumors face high morbidity and mortality, yet often do not receive palliative care (PC). There is evidence of the benefit of PC in pediatric oncology, though the ideal timing remains unknown. We aimed to evaluate the feasibil...

Safety and satisfaction of voluntary medical male circumcision among men who have sex with men in China

PURPOSE: To investigate the safety and satisfaction of circumcision among men who have sex with men (MSM), as voluntary male medical circumcision (VMMC) may be an innovative and acceptable tool for HIV prevention among this population in the future. METHODS: Participants who volu...

Integrative molecular identification and mitochondrial genetic diversity of cryptic Anopheles vectors in malaria hotspots of northwestern Thailand

The Anopheles barbirostris complex comprises several sibling species capable of transmitting malaria and lymphatic filariasis and is increasingly recognised as a potential contributor to residual malaria transmission in the Greater Mekong Subregion (GMS). However, the morphologic...

Personal networks and cognitive health across rural-urban contexts

Abstract Objectives Prior research often reports geographic cognitive health disparities in later life, including across rural-urban contexts. Yet few studies have examined the role of personal social networks in shaping these geographic disparities. This study investigates wheth...

Insights into Microbiota–Vaccine Crosstalk in Humans: Mechanisms, Modulators, and Translational Horizons

Vaccine responses differ substantially among individuals and across populations. Although factors such as age, genetics, and vaccine type are recognized contributors, they do not fully explain this heterogeneity. Emerging evidence suggests that the human microbiota, particularly...

Depth-Dependent Interplay of Dynamical Heterogeneity and Chain Dynamics at the Surface of Glass-Forming Polymers

Abstract Polymer thin films exhibit pronounced interfacial mobility gradients that modify chain relaxation, yet how these gradients govern chain-scale dynamics across depth remains incompletely understood. Using molecular dynamics simulations of freestanding glass-forming polymer...

Binary Darboux transformations for a skew-symmetric matrix integrable nonlinear Schrödinger equation

The aim of this article is to construct a class of binary Darboux transformations for a skew-symmetric matrix integrable nonlinear Schrödinger equation. The associated AKNS-type Lax pairs, corresponding to the orthogonal Lie algebra so(2m), provide the framework necessary for sys...

Maternal dimethoxyethyl phthalate exposure enhances nicotine challenge-induced locomotor sensitization in adult male offspring rats: role of striatal dopamine D1 receptor

Early-life exposure to environmental endocrine disruptors, such as phthalates and bisphenol A, has been linked to neurobehavioral disorders, including autism spectrum disorder and attention-deficit/hyperactivity disorder (ADHD). Recent studies have also reported that individuals...

Non-English Primary Language Is Associated With Lower Odds of Non-home Discharge After Trauma: A Retrospective Cohort Study at a Level I Trauma Center

Language barriers may influence trauma care and outcomes. This study evaluated the impact of primary language on clinical care factors and outcomes in adult trauma patients via retrospective review from 2019 to 2023. Patients were stratified as English primary language (EPL) or n...

Safety and Performance of the Colovac Anastomosis Protection Device. A Pooled Analysis of Prospective Studies Compared With Diverting Loop Ileostomy (SAFE-2025)

Objective: To compare the safety and effectiveness of the Colovac Anastomosis Protection Device with standard diverting ostomy (DO) following low anterior resection (LAR) for rectal cancer. Summary Background Data: DO is standard of care (SOC) following LAR for rectal cancer but...

Gut Microbiota and Brain Aging: Identifying Keystone Biomarkers for Cognitive Health

The fact that the population is getting older has greatly increased the occurrence of cognitive decline and neurodegenerative diseases, underlining the importance of having reliable biomarkers that can measure biological aging before irreversible neurological damage takes place....

Rationale and study design for the Social Environment and Cognitive Health in Urban and Rural Areas Study

Abstract Objective The Social Environment and Cognitive Health in Urban and Rural Areas study was designed to examine cognitive health disparities in later life. It gathers data on access to social resources, engagement in cognitively stimulating interactions, and exposure to act...

Superlarge-Bore Versus Large-Bore Aspiration Catheters in Mechanical Thrombectomy: A Multicenter Propensity-Matched Analysis

BACKGROUND AND OBJECTIVES: Aspiration catheters are an integral component of mechanical thrombectomy for acute ischemic stroke (AIS). Following early series demonstrating increasing procedural efficiency and improved outcomes with use of large-bore (LB) aspiration catheters, ther...