University of Rochester

Local Adaptations of Hospital in Home: Variations in Structure and Implementation Across Six VA Programs

ABSTRACT Background The VA Hospital in Home (HIH) model of care delivers acute‐level hospital care to Veterans at home across the country. We aim to examine the similarities and differences in the structure and implementation of existing HIH programs across sites to identify best...

PD GENEration: an international Parkinson’s disease genetic research study

Abstract Background PD GENEration (NCT04057794, NCT04994015), sponsored by the Parkinson's Foundation in partnership with Aligning Science Across Parkinson’s (ASAP) through the Global Parkinson’s Genetics Program (GP2), is an international, observational, clinical research study...

Raman Spectroscopic Characterization of the Benzene:Acetonitrile (3:1) Cocrystal Relevant to Titan, Saturn’s Moon

Abstract Titan, Saturn’s largest moon, hosts active organic chemistry and surface environments where small molecules are expected to crystallize as molecular minerals. Benzene and acetonitrile, both predicted to be present on Titan, were shown to form a thermodynamically stable b...

Design and Commissioning of a Deuterium-Tritium Gas Delivery System for Muon-Catalyzed Fusion in a Diamond Anvil Cell

We report the design, commissioning, and operation of deuterium-deuterium (DD) and deuterium-tritium (DT) gas delivery systems developed to load a diamond anvil cell (DAC) beam target for muon-catalyzed fusion (µCF). The DAC approach enables DT fuel to be compressed to gigapascal...

Predictors of Delayed and Omitted Postoperative Radiotherapy After Laryngectomy for pT4 Laryngeal Cancer

BACKGROUND: Postoperative radiotherapy (PORT) improves locoregional control and survival in high-risk head and neck cancer, and guidelines recommend initiation within 42 days of surgery. Timeliness after laryngectomy for pathologic T4 (pT4) laryngeal cancer is poorly characterize...

Fundamentals of Arthroscopic Surgery Training Program Shows Transfer Validity Through Enhanced Operative Arthroscopic Performance

PURPOSE: To evaluate the content, construct, concurrent, and transfer validity of the Fundamentals of Arthroscopic Surgery Training (FAST) program and to determine whether FAST testing performance correlated with arthroscopic performance in the operating room. METHODS: Participan...

Closeness and Well-Being in Older Adulthood: A Dyadic Daily Diary Study

Relationships are central to well-being. Relationship closeness, which measures interdependence, remains underexplored in older adult couples managing chronic health conditions. In a sample of 146 distinguishable dyads consisting of individuals with chronic back pain (ICBPs) and...

Pressure-driven structural phase competition and functional response in layered LiInP2S6

Understanding how hydrostatic pressure modifies interlayer interactions and competing ionic configurations is essential for controlling the emergent functional properties of layered quantum materials. Here, using first-principles density-functional theory calculations, we investi...

Coordination Chemistry of Thorium Supported by a Single Polyoxoalkoxide Ligand

Abstract Actinide-polyoxometalate (An-POM) literature is dominated by the formation of 1:2 An(POM)2 sandwich-type complexes. Here, we report selective formation of a 1:1 An-POM complex using non-aqueous methods. Treatment of the lacunary POM precursor, (TBA)2[Mo5O13(OMe)4NO][Na(M...

Prenatal exposure to wildfire fine particulate matter and fetal growth outcomes in the United States: Findings from the ECHO Cohort

Background: Increasing exposure to wildfire fine particulate matter (PM 2.5 ) may pose unique risks to fetal development. We assessed associations between prenatal wildfire PM 2.5 exposure and fetal growth outcomes, including birth weight at term, birth weight for gestational age...

Individual and school determinants of collective teacher innovativeness: a multilevel analysis

Collective teacher innovativeness is the team-level propensity perceived by teachers to seek, develop, and implement new pedagogical practices and is a pivotal factor for successful educational reforms. This study investigates multilevel factors contributing to collective teacher...

Mapping Cellular Senescence, Cellular Plasticity, and Alveolar Niche Heterogeneity in Human Lung Development

This repository contains the code, workflows, and source files used for the analyses presented in the manuscript. Contents Preprocessing and integration of pediatric lung snRNA-seq datasets Harmony integration and Azimuth annotation workflows Cell proportion analyses Differential...

Perceived pleasantness mediates the effects of high-arousal and emotionally complex music on pain

ABSTRACT: Music effectively reduces pain, yet the mechanisms underlying music-induced hypoalgesia remain poorly understood. We investigated how latent perceptual dimensions of music influence pain by examining both stimulus properties and subjective evaluations of those propertie...

Prevalence and Characteristics of Mental Health Interventions Following Pediatric Hospitalization

BACKGROUND AND OBJECTIVES: As survival after pediatric critical illness improves, attention has shifted to post-intensive care syndrome and the long-term mental health of pediatric intensive care unit (PICU) survivors, who have high rates of posttraumatic stress, anxiety, and dep...

Factors Influencing Caregiver Anxiety in the Pediatric Emergency Department

OBJECTIVES: This study identified demographic and experiential factors associated with caregiver anxiety in a pediatric emergency department (PED). METHODS: We conducted a cross-sectional survey of caregivers for children brought to our PED. Participant anxiety was assessed with...

Window-of-Opportunity Study Utilizing Preoperative Cetuximab in Patients with Head and Neck Cancer

Abstract Purpose. AXL, is a receptor tyrosine kinase implicated in EGFR resistance. The primary objective of this study was to test the hypothesis, generated in preclinical studies, that low AXL correlates with clinical response to cetuximab in patients with head and neck cancer...

Towards More Nuanced Research Designs to Study AI Adoptions: An Illustration from the Field of Music

To illustrate the importance and complexity of considering “task–technology fit”, as well as users’ roles and purposes, when studying AI adoption within any occupation, we present findings from a 2023-25 mixed-method study about professional musicians’ uses and perceptions of AI...

Identifying Contextual Factors affecting Hospital In Home Program Implementation within the Veterans Health Administration

Abstract Background and Objectives Understanding the factors that enable or hinder successful implementation is essential for improving patient outcomes. Hospital in Home (HiH) programs provide hospital-level care in patients' homes to reduce hospitalization, enhance satisfaction...

Collusion through Common Leadership

This paper studies whether common leadership, defined as two firms sharing executives or board directors, contributes to collusion. Using an explicit measure of labor market collusion from unsealed court evidence, we find that the probability of collusion between two firms increa...

What one sees depends on how far the eye has moved

Humans explore visual scenes through frequent, rapid gaze shifts known as saccades. These movements redirect the high-acuity region of the retina toward objects of interest, thus selecting information based on location. Here, we show that saccade amplitude provides a separate and...