University of Missouri–Kansas City

E-cigarette use and nicotine dependence among hospitalized youth: influence of nicotine metabolism and CYP2A6 variability

Background Youth e-cigarette use is a public health concern, yet cessation approaches remain suboptimal. In adults, faster nicotine metabolism is linked with better cessation outcomes with varenicline compared to nicotine replacement therapy (NRT). This remains unexplored in yout...

Gender Similarity in Hierarchical Work Relationships: A Meta‐Analysis

ABSTRACT Hierarchical work relationships, such as mentoring and supervisor relationships, provide access to key resources that promote employee well‐being and effectiveness. As such, scholars have investigated factors that enable relational success, with gender similarity being a...

Reduced dosage of Kmt2d modifies Tbx1 haploinsufficiency toward phenotypes of 22q11.2DS

Haploinsufficiency of TBX1 , which occurs in 22q11.2 deletion syndrome (22q11.2DS), leads to a heterogeneous spectrum of clinical manifestations, including craniofacial anomalies, immunodeficiency, and congenital heart defects. The variability in syndromic presentation between pa...

Empiric MRSA Coverage for Children with Osteoarticular Infections: 2015 to 2024

BACKGROUND AND OBJECTIVES Staphylococcus aureus is the most common causative pathogen for children with acute hematogenous osteomyelitis (AHO) and acute bacterial arthritis (ABA). National guidelines recommend empiric coverage for methicillin-resistant S. aureus (MRSA) at hospita...

Anatomical versus reverse total shoulder arthroplasty for primary glenohumeral osteoarthritis with an intact rotator cuff

Aims Anatomical total shoulder arthroplasty (aTSA) has been the traditional treatment for glenohumeral osteoarthritis (OA) with an intact rotator cuff. However, reverse total shoulder arthroplasty (rTSA) is now being more frequently performed, with its utility in consistent fixat...

Controversies in the management of fetal growth restriction: a state-of-the-art review

Fetal growth restriction (FGR) affects 5%-10% of pregnancies and remains a major contributor to stillbirth, neonatal morbidity, and long-term adverse outcomes. Despite its clinical importance, substantial controversy persists regarding its definition, diagnostic criteria, surveil...

Children With Complex Chronic Conditions in the Child Protective Services

OBJECTIVES: Little is known about the prevalence and outcomes for children with complex chronic conditions (CCCs) in the Child Protective Services (CPS) system. We aimed to determine the prevalence and associations of CCC designation across CPS outcomes and years among a group of...

Caregiver Perspectives on Implementation of Discharge Plans for Children With Medical Complexity

OBJECTIVE The quality of discharge processes impacts adverse outcomes post hospitalization for children with medical complexity (CMC). Perspectives of caregivers at risk for communication challenges (eg, non-English speakers, those with limited health literacy, immigrants) on und...

DIFFRACTION Abstract Asymmetrical Systems Modeling

DIFFRACTION: Abstract Asymmetrical Systems Modeling is the third manuscript in the DIFFRACTION research program. This work formalizes a framework for modeling asymmetrical systems whose state identity is preserved through reversible, admissibility-constrained transformations. The...

Losing All Faith in Women’s Healthcare: Experiences of Living with Chronic Pelvic Pain After Pelvic Congestion Syndrome Treatment

Objectives: The purpose of this study was to describe the experiences of women with pelvic congestion syndrome (PCS). We aimed to (1) explore the experiences before receiving a PCS diagnosis, (2) describe the experience of being diagnosed and living with PCS, and (3) identify cha...

DIFFRACTION Abstract Asymmetrical Systems Modeling

DIFFRACTION: Abstract Asymmetrical Systems Modeling is the third manuscript in the DIFFRACTION research program. This work formalizes a framework for modeling asymmetrical systems whose state identity is preserved through reversible, admissibility-constrained transformations. The...