University of Medicine and Pharmacy at Ho Chi Minh City

Screening strategies for the early detection of non-cardia gastric cancer in low- to moderate-prevalence regions: Asia-Pacific gastroesophageal cancer congress consensus 2026

Abstract Background Gastric cancer (GC) remains a major global health burden, and early detection is essential for improving patient outcomes. Although GC screening has been widely implemented in East Asian countries with a high disease burden, the optimal screening strategy for...

Surgical Outcomes of Terrible Triad Injuries of the Elbow in a Resource-Limited Setting: A Consecutive Case Series

Purpose To evaluate surgical outcomes of acute terrible triad injuries of the elbow treated without radial head prostheses or hinged external fixation and to identify factors associated with recovery in a resource-limited setting. Methods We retrospectively reviewed 30 of 151 eli...

Perceived Time Availability for Self-Care and Quality of Life in Patients with Major Depressive Disorder: A Cross-Sectional Study in Ho Chi Minh City, Vietnam

Background: Major depressive disorder (MDD) severely impairs quality of life (QoL), yet contextual constraints such as perceived time availability for self-care remain underexplored in low- and middle-income countries. This study evaluated multidimensional QoL and identified its...

Psychometric validation of the Vietnamese Hospital Anxiety and Depression Scale (HADS) in adults with type 2 diabetes mellitus: a multi-site cross-sectional study

Anxiety and depression are common in type 2 diabetes mellitus (T2DM) and are associated with poorer self-management and clinical outcomes. This study evaluated the measurement properties of the Vietnamese Hospital Anxiety and Depression Scale (HADS) in adults with T2DM. In this m...

Post‐COVID‐19 Public Health Challenges: Insights Into Post‐COVID Symptoms, Stigma, and Post‐Pandemic Recovery Support From the Vietnam Experience

ABSTRACT Objectives This study aimed to assess the burden of post‐COVID‐19 symptoms, social stigma, and quality of life, and to examine their interactions among individuals recovering from COVID‐19 in Vietnam. Methods A cross‐sectional survey was conducted from March to June 2022...

Clinical, radiographic and microbiological manifestations of newly diagnosed pulmonary tuberculosis across CD4 strata in adults with advanced HIV disease: a real-world cross-sectional study in southern Vietnam

Abstract Background In advanced HIV disease, pulmonary tuberculosis (PTB) presents atypically and overlaps clinically, radiographically and microbiologically with Pneumocystis jirovecii pneumonia and bacterial infection. We describe these three axes across CD4 strata in adults wi...

Clinical and radiographic evaluation of MTA Flow™ thick as a retrograde filling material in apicoectomy: a preliminary study

OBJECTIVE: To date, limited evidence exists regarding the clinical efficacy of MTA Flow™ Thick as a retrograde filling material in apicoectomy. This study aimed to investigate the clinical and radiographic outcomes over a 6-month follow-up period following apicoectomy with MTA Fl...

The Efficacy of a Manual Microfluidic Dish Compared with the Discontinuous Gradient Centrifugation Method for Sperm Selection in ICSI Cycles

Introduction: Microfluidic sperm selection systems (MFSSs) have emerged as centrifugation-free alternatives to conventional sperm preparation methods, such as density gradient centrifugation (DGC), which may induce oxidative stress and sperm DNA damage. Although commercial MFSS d...

Comparison of pain perception and autonomic stress response during dental anesthesia: a split-mouth randomized clinical trial of computer-controlled versus conventional local anesthetic delivery

Anxiety remains a primary barrier to dental care and is often triggered by injections. Although computer-controlled local anesthetic delivery (CCLAD) is used to mitigate distress, previous research has been limited by methodological shortcomings. This split-mouth randomized trial...

The future of allergy and immunology care: A perspective on innovation, equity, and global collaboration from the WAO Junior Members Group

Allergic and immunological diseases are among the fastest-growing non-communicable conditions worldwide, affecting all age groups and regions.1 The increasing burden of asthma, allergic rhinitis, atopic dermatitis, food allergy, and other immune-mediated conditions is driven by c...

Neurodevelopmental Trait Subgroups in Medically Unexplained Oral Symptoms: A Retrospective Observational Study

Introduction and aims Medically unexplained oral symptoms (MUOS) are heterogeneous conditions with prominent subjective complaints despite limited objective findings. We examined whether autism spectrum disorder (ASD)- and attention-deficit/hyperactivity disorder (ADHD)-related t...

Balancing altruism, risk and ethics: Vietnamese students’ views on human challenge studies

Introduction Human challenge studies (HCS) have been proposed to accelerate the development of health interventions and strengthen research capacity in low- and middle-income countries. However, implementation in settings such as Vietnam, where clinical care facilities and resear...

Prevalence and associated factors of cognitive impairment in patients with major depressive disorder: a cross-sectional study in Vietnam

Objective Cognitive impairment is increasingly recognised as a core feature of major depressive disorder (MDD), but data from low- and middle-income countries, including Vietnam, remain scarce. This study examined the prevalence of cognitive impairment among patients with MDD and...

22q11.2 microdeletion and immunological status of Vietnamese children with tetralogy of Fallot and pulmonary atresia with ventricular septal defect

The 22q11.2 deletion (22q11.2Del) is one of the most common chromosomal microdeletions associated with a broad range of clinical manifestations, including congenital heart disease and immunodeficiency. Several studies reported a high frequency of 22q11.2Del in patients with conot...

Chronic trans-rectal impalement with jejunal and duodenal perforations in a young child: a case report

Rectal penetrating trauma is a rare but potentially life-threatening injury in children. Diagnosis is challenging, especially when external signs are minimal or when clinical manifestations appear in a delayed fashion. We describe a 46-month-old Vietnamese girl with a complex cli...

Complete androgen insensitivity syndrome in two siblings with a pathogenic androgen receptor gene variant: a case series

Complete androgen insensitivity syndrome (CAIS) is a rare X-linked disorder caused by pathogenic variants in the androgen receptor (AR) gene, resulting in complete resistance to androgen action in individuals with a 46,XY karyotype. Familial cases of CAIS provide important insigh...

Changes in depressive symptoms and disordered eating attitudes and behaviors during antidepressant treatment among Vietnamese patients with major depressive disorder

Major Depressive Disorder (MDD) is linked to appetite and weight disturbances. While antidepressants (ADs) stabilize mood, their impact on psychological eating attitudes and behaviors remains underexplored. This study aimed to investigate longitudinal changes in mean EAT-26 total...

Airway management in retrosternal goiter surgery: a five-year single-center retrospective observational study in a low-resource setting

Abstract Background Retrosternal goiter can cause tracheal deviation, airway compression, and recurrent laryngeal nerve dysfunction, posing challenges for perioperative airway management. Evidence guiding airway management strategies is largely derived from high-resource settings...

A CD44-targeted PDA/ZnO redox-active nanocomposite that couples chemotherapy with mitochondrial stress and tumor immune remodeling

Bladder cancer therapy is frequently limited by inefficient drug retention and adaptive immune resistance within a hypoxic tumor microenvironment. Here, we report a CD44-targeted, fully synthetic nanocomposite (HPPZC) that converts chemotherapy into a mitochondria-associated ther...

Anti-MDA5-associated rapidly progressive interstitial lung disease in clinically amyopathic dermatomyositis with secondary invasive pulmonary Aspergillus flavus infection after aggressive immunosuppressive therapy: a case report

Anti-melanoma differentiation-associated gene 5 (MDA5) positive rapidly progressive interstitial lung disease (RP-ILD) with clinically amyopathic dermatomyositis (CADM) is a life-threatening condition. Prompt initiation of immunosuppressive therapy is crucial for improving outcom...