University of L'Aquila

Surface Termination Unlocks Photocatalytic Potential: Reshaping Structure and Electronics in Ultrathin MoS 2 /TiO 2 Heterojunctions

Anatase TiO 2 stands out for its exceptional chemical stability, nontoxicity, and robust photocatalytic capabilities; however, its intrinsically wide bandgap severely restricts its activity to the ultraviolet spectrum, limiting practical efficiency under solar illumination. To ci...

In the wisdom of Odin: modular architecture, receptor trafficking and therapeutic implications

Odin (ANKS1A) is a multidomain adaptor protein originally identified as a substrate of receptor tyrosine kinases. Over the past two decades, studies have revealed functions that extend beyond canonical growth factor signaling. At the molecular level, Odin participates in receptor...

Object‐Control Skills and Cortisol Response During Physical Education Lessons in Primary School Children

BACKGROUND: Object-control (OC) skills are fundamental movement skills acquired during primary school that may act as either stressors or engagement factors during physical education (PE). This study examined the acute impact of OC exercises on children's stress levels across gra...

A Geometric Characterization of Maximal Unrefinable Partitions via the Keith–Nath Transformation and Young Diagrams

Abstract We investigate the combinatorial structure of unrefinable partitions through their correspondence with numerical sets and Young diagrams. Building on the bijection introduced by Keith and Nath, we apply a general geometric criterion that links the unrefinability of a par...

Real-world effectiveness and drug retention rate of risankizumab in patients with psoriatic arthritis: data from the multicentre GIRRCS cohort

Introduction Psoriatic arthritis (PsA) is a chronic heterogenous inflammatory disease characterized by a multidomain burden. Risankizumab, a selective inhibitor of the IL-23 p19 subunit, has shown efficacy in randomized trials; however, real-world data in PsA remain limited. We e...

Stripping‐based approach for the recovery of volatile fatty acids from anaerobic digestion digestate: preliminary experimental investigations and modelling

Abstract BACKGROUND Volatile fatty acids (VFAs) are widely used across industries: as intermediates in chemical production (e.g . , solvents and polymers), in pharmaceuticals and cosmetics, and as preservatives and health‐promoting additives in food and animal feed. Emerging appl...

Molecular Engineering of Aptamers for Glioblastoma Therapy: From Simple Antagonists to AI-Driven Approaches, a Narrative Review

Glioblastoma multiforme (GBM) is an extremely aggressive and lethal brain tumor, characterized by marked molecular heterogeneity, the persistence of glioma stem cells (GSCs), and the limited permeability of the blood–brain barrier (BBB), which collectively hinder therapeutic effi...

Zero-Dimensional Bismuth Halide Thin Films with High Orientation and Broadband Emission

Abstract Lead-free low-dimensional metal halides are emerging as highly tunable materials for optoelectronic applications. Here, we report a new class of zero-dimensional bismuth halides incorporating phenethylammonium (PEA) cations, namely PEA4BiI7 and PEA4BiBr7, and investigate...

The Mast Cell–Substance P Neuroimmune Axis in Allergic Contact Dermatitis and Atopic Dermatitis: Molecular Mechanisms and Pathophysiological Perspectives

Recent advances in cutaneous neuroimmunology have substantially expanded our understanding of inflammatory skin diseases, revealing an intricate bidirectional network linking peripheral sensory neurons, resident immune cells, and structural skin components. Among the mediators or...

Lean Mass Reduction During Glucagon-like Peptide-1 Receptor Agonists-Induced Weight Loss: Rethinking Its Clinical Significance

The substantial weight loss achieved with glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and dual incretin agonists has transformed the management of obesity and cardiometabolic risk. However, the accompanying reduction in lean mass has raised concerns regarding potential...

Unconventional Materials for Light Dark Matter Detection

We propose the use of several unconventional materials as detectors for dark matter with mass beneath the MeV scale. These include the transition-metal dichalcogenide TiSe 2 hosting a low-energy plasmon in the charge-density-wave phase, Sr 2 RuO 4 containing a low-energy acoustic...

Hospital Admissions for Respiratory Syncytial Virus (RSV) Among Elderly: A Retrospective Study From an Italian Southern Region During Years 2018–2023

ABSTRACT Introduction Respiratory syncytial virus (RSV) is one of the most common causes of acute respiratory infections in both children and adults over 60. RSV can cause severe lower respiratory tract infections in older adults, leading to an increase of morbidity and mortality...

HPV DNA negativity following AHCC or nonavalent vaccination or their combination in women with persistent HPV infection without HSIL

Persistent infection with high-risk human papillomavirus (HR-HPV) is a common clinical condition for which no validated systemic antiviral therapy is currently available, and in the absence of high-grade cervical lesions management is generally limited to surveillance. Active Hex...

Salivary hormones and adipokines are associated with glycemic control and early renal and cardiometabolic markers in children and young adults with type 1 diabetes

Abstract Purpose Type 1 diabetes (T1D) is recognized as a complex metabolic condition associated with hormonal dysregulation and early complications. This study aimed to evaluate salivary metabolic hormones and adipokines in children and young adults with T1D, and to assess their...

Preliminary Clinical Outcomes of an Alternating-Current-Assisted Implant Surface Decontamination Protocol: A Prospective Case Series with 12-Month Follow-Up

Background: Treatment of peri-implantitis remains challenging because biofilm removal from microstructured implant surfaces is often incomplete. The present study is an uncontrolled, prospective feasibility case series involving six patients (six implants), not a controlled clini...

Multi-model high-resolution analysis of Tropical-Like Cyclone Daniel with WRF and ICON: peculiarities and sensitivity to convection schemes

Abstract. Medicane Daniel (September 2023) featured a rapid transition from a baroclinic disturbance to a compact tropical-like vortex, challenging short-range prediction. This study delivers a side-by-side, high-resolution (∼2 km) assessment of Daniel using two state of the art...

Physics-based 3D ground motion simulations of the 1703 L’Aquila earthquake: from historical reconstruction to seismic scenarios

Abstract The city of L’Aquila (central Italy) and its surrounding villages have been struck several times throughout history by strong earthquakes, most recently by the $$M_w$$ M w 6.1 event of April 6, 2009. Previously, on February 2, 1703, L’Aquila was partially destroyed by a...

XR in cultural heritage: a comparative study of motivation, presence, and engagement across 360° virtual tours, VR, and AR at the archaeological site of Villa Regina

Abstract As immersive technologies gain prominence in cultural heritage, understanding their specific experiential qualities has emerged as a central research challenge. This study presents a rigorously controlled comparative analysis of three immersive systems: virtual reality (...

Decoding the causes of ischemic stroke despite ongoing oral anticoagulation and their clinical impact: the ASPERA-R study

BACKGROUND: Oral anticoagulants (OACs), including vitamin K antagonists and direct OACs, reduce stroke risk in atrial fibrillation (AF), yet breakthrough ischemic stroke still occurs in 1-2% of patients annually despite adequate therapy. The mechanisms underlying these events rem...

Widespread thermophilization but weak link to climate warming in Europe’s summit plant communities

Abstract Recent changes in alpine vegetation are often attributed to climate warming, particularly community composition shifts towards more warmth-associated species, or thermophilization. Here we assess the link between thermophilization and warming across 53 European mountain...