University of Kinshasa

Tribute: Dr. Charles Mbusa Munyumu – killed in action for neurosurgery

On August 10, 2026, Dr. Charles Mbusa Munyumu died of Ebola virus disease in Butembo, North Kivu, Democratic Republic of the Congo. He had contracted Bundibugyo virus while operating on a patient. He was 48, had qualified in neurosurgery in Dakar, and had returned home only month...

Impact of praziquantel treatment and early reinfection patterns in a mixed Schistosoma mansoni and Schistosoma haematobium infection focus in the Democratic Republic of Congo

Objective To evaluate the impact of single versus mixed Schistosoma infections on the efficacy of PZQ treatment as well as on the dynamics of reinfection after treatment. Methods We followed 388 randomly selected residents of a village co‑endemic for Schistosoma haematobium and S...

Endogenous anti-Ebola virus GP 1,2 antibodies interfere with detection of secreted glycoprotein in the blood of EVD patients

ABSTRACT Ebola disease (EBOD) is a highly infectious disease with severe hemorrhagic symptoms. It is caused by orthoebolaviruses , which include the Ebola virus ( Orthoebolavirus zairense ) (EBOV) causing Ebola virus disease (EVD), the most lethal EBOD to humans. Through co-trans...

Extraction dataset, risk-of-bias assessments and analysis code for Incremental value of integrating histopathology with omics for prediction in non-small-cell lung cancer: a systematic review and meta-analysis

This record contains the data and code supporting the systematic review and meta-analysis "Incremental value of integrating histopathology with omics for prediction in non-small-cell lung cancer: a systematic review and meta-analysis" (submitted to Briefings in Bioinformatics). T...

Early insights into predicted efficacy of Ebola monoclonal antibodies for the 2026 Bundibugyo virus disease outbreak

The 2026 Bundibugyo virus disease (BVD) outbreak in the DRC and Uganda raises urgent questions about the efficacy of existing Ebola virus (EBOV) monoclonal antibodies (mAbs) against Bundibugyo virus (BDBV). Here, we perform genomic and structural analyses of 44 BDBV sequences, in...

A Two-Stage Framework for Sports Betting Asset Construction: Probabilistic Prediction and Risk-Aware Portfolio Allocation

This manuscript presents a two-stage framework that treats sports betting markets as an alternative asset class, coupling probabilistic prediction with risk-aware portfolio allocation. The first stage produces calibrated probabilistic forecasts of match outcomes using heterogeneo...

Detecting and Localizing Generated Segments in French-Language Hybrid Texts through Within-Document Variance of Linguistic Features

Research protocol / preprint. This manuscript presents a proposed methodology; no experiments, performance measurements, or improvements are claimed. Results remain to be completed after experimentation. Document-level classification is insufficient when human-written and AI-gene...

Mamba-OrthoNet: unified global–local feature fusion and angular encoding for accurate ship orientation detection

Abstract Accurate ship orientation detection in high-resolution remote-sensing imagery is vital for maritime monitoring, traffic management, and search-and-rescue. Yet port scenes are crowded and ships vary in scale: global context separates adjacent ships, while fine local cues...

Hybrid deep learning for smart grid SCADA intrusion detection with mutual information feature selection for smart meter data analysis

The rapid evolution of smart grid infrastructure has intensified the dependence on SCADA-based supervisory systems for real-time energy management, grid reliability monitoring, and seamless integration of renewable energy sources. However, the growing digitalization of these cybe...

Measurement of binding antibodies to SARS-CoV-2 variants elicited by natural infection and COVID-19 vaccines in a sub-Saharan African population

Abstract Data on immune responses to COVID-19 vaccination in West and Central Africa remain limited, particularly with respect to antibody (Ab) binding across SARS-CoV-2 variants and for different types of vaccine platforms. We assessed anti-spike (anti-S) antibody binding to nin...

Family planning self-care: From global frameworks to local meaning, perceptions, experiences and opportunities in Niger

Abstract Family planning (FP) self-care is a strategic pillar for advancing Universal Health Coverage (UHC) and mitigating health workforce shortages. However, a significant disconnect persists between global normative frameworks and local implementation realities. This study exa...

Synergy of surface oxygen vacancies and built-in electric field in 0D/2D CeO2/SnSe2 S-scheme heterojunctions for enhanced photocatalytic malachite green degradation

Abstract Industrial effluents exacerbate aqueous contamination, necessitating the urgent remediation of toxic dyes such as Malachite Green (MG). In this study, a 0D/2D S-scheme heterojunction was constructed by anchoring CeO 2 nanocubes onto SnSe 2 hexagonal nanosheets via a prec...

Influence of spatial connectivity on the spread of Mpox in Maï-Ndombe province, Democratic Republic of the Congo, 2025

<title>Abstract</title> <bold>Background</bold> The spread of Mpox in the DRC is strongly influenced by human mobility in a context of environmental constraints and inequalities in accessibility. The province of Maï-Ndombe, with its fragmented transport network and dependence on...

One in seven has severe pain: a point-prevalence study of hospitalised patients across Africa

ABSTRACT: Acute pain in hospitalised patients is common, yet African data are scarce. We conducted a prospective point-prevalence study of hospitalised adult patients across Africa to determine acute pain prevalence and severity and investigate associations of pain with critical...

Evidence of dengue transmission and a diverse Aedes mosquito virome on the Congo’s Angola border

Abstract Aedes mosquitoes are widely distributed across the Democratic Republic of Congo (DRC), and are major vectors of dengue (DENV), Zika, chikungunya (CHIKV), and yellow fever (YFV) viruses. While the high burden of malaria in the DRC receives considerable attention, arboviru...

The World Psychiatric Association (WPA) Guideline on Schizophrenia Spectrum Disorders Management for Low- and Middle-Income Countries

There is a pressing need to address the unique challenges of managing Schizophrenia Spectrum Disorders (SSD) in Low- and Middle-Income Countries (LMICs), where mental health resources are scarce and unevenly distributed. To develop this evidence-based guideline, we conducted a sy...

SARS-COv-2, influenza and other respiratory virus co-circulation during an outbreak in a rural health zone in Democratic Republic of Congo, 2024–2025

Little is known about the global impact of co-circulation and co-infection of COVID-19 and influenza in Democratic Republic of the Congo (DRC). This study aims at analyzing data on SARS-CoV-2, influenza and other respiratory viruses collected during an outbreak response in the ru...

Geochemical assessment of metal and REE concentrations in a region with exploration of petroleum resources, Democratic Republic of the Congo

The Lemba petroleum sub-basin in the western Democratic Republic of the Congo was investigated to assess the composition of soils and riverbed sediments, the concentrations of contaminants and the environmental pollution hazards derived from the ongoing oil exploration and other...

Albuminuria and associated renal and hemodynamic factors in adults with steady-state sickle cell disease: a multicenter study with measured GFR

Albuminuria is an early marker of renal involvement in sickle cell disease (SCD) and is associated with progressive renal function decline. However, data on albuminuria in adults with SCD in sub-Saharan Africa remain limited. This study aimed to determine the prevalence of albumi...