University of Kigali

Microclimatic effects on activity patterns in a montane chimpanzee population

Abstract Climatic variation can shape primate activity budgets by altering the energetic and thermoregulatory costs of feeding, resting, locomotion and social behaviour. However, little is known about how chimpanzees that inhabit cool, wet montane forests adjust their activity in...

Assessment of growth and survival rate of native tree species across COMBIO project areas in Eastern Province of Rwanda

Abstract Restoration of degraded land and deforested landscapes using native tree species has been claimed important in addressing global environmental challenges. In Rwanda, the COMBIO project aims at restoring the degraded lands and forests in the Eastern Province using native...

Collaborative clinical research ethics and regulatory governance in Sub-Saharan Africa: Gaps, challenges and implications

Although some countries in sub-Saharan Africa have strengthened their systems and reached WHO GBT Maturity Level 3, important gaps remain. Addressing these gaps is critical for strengthening clinical research oversight and preparedness. This open letter highlights that ethics and...

The impact of financial inclusion on economic growth in Uganda from 1986 to 2022

This study evaluates the impact of financial inclusion on economic growth in Uganda, using 37 years of annual data (1986–2022) obtained from the World Development Indicators database. We estimate financial inclusion (in terms of domestic credit to the private sector) as a percent...

Quality and concordance of international paediatric sepsis guidelines: a cross-sectional appraisal from the SENTINEL International study

Objectives To evaluate the methodological quality of hospital-specific paediatric sepsis clinical practice guidelines (CPGs) from sites participating in an international study using the Appraisal of Guidelines for Research and Evaluation II (AGREE II) tool and to assess the consi...

Workflow management systems and reproducible pipelines for Plasmodium falciparum genomic surveillance: tools, design principles and infrastructure challenges

Genomic data are increasingly leveraged to enable malaria genomic surveillance, with many teams now generating Plasmodium falciparum sequence data for routine analysis. However, downstream analysis remains dependent on ad-hoc scripts and local infrastructure. This reliance limits...

Prevalence of burnout among practising anaesthesia providers: a systematic review

Summary Introduction Burnout is characterised by emotional exhaustion, depersonalisation and reduced personal accomplishment. Anaesthesia providers are at particular risk of experiencing burnout, with implications for workforce well‐being and patient safety. We aimed to quantify...

Histological placental abnormalities and associated factors among malaria smear-positive women delivering at two tertiary hospitals in Uganda: a comprehensive multicenter cross-sectional study

Malaria in pregnancy may disrupt placental structure and function, but evidence describing placental abnormalities among malaria-positive women in Uganda remains limited. This study determined the prevalence and patterns of gross and histological placental abnormalities and exami...

Boosted training strategy for physics-informed neural networks in modeling non-linear computer virus dynamics with vertical transmission

Computer-virus propagation in networked systems is often modeled by epidemic-type derivative equations. Still, standard quantitative solvers can become computationally demanding and may exhibit small stability for long-term predictions. This work develops a Physics-Informed Neura...

Antimicrobial stewardship in practice: determinants of prescription behaviour and developing interventions to improve surgical prophylaxis in a Rwandan tertiary hospital—a mixed methods study using the behaviour change wheel

BACKGROUND: Behavioural sciences should be used to design and improve antimicrobial stewardship (AMS) interventions aiming surgical prophylaxis (SP). METHODS: A mixed-methods study at the University Teaching Hospital of Kigali, Rwanda. The study included an audit on SP practices...

Assessment of unsuppressed viral load and its determinants among pregnant and breastfeeding women living with HIV in the prevention of vertical transmission programme in Bugesera District, Rwanda, 2023

Abstract Background Prevention of vertical transmission (PVT) of HIV programs are designed to prevent the transmission of HIV during pregnancy and breastfeeding. Nevertheless, attaining viral suppression among mothers living with HIV remains a major challenge, especially in resou...

Bilateral ascending dry gangrene following documented smear-positive malaria in a patient with multivalvular rheumatic heart disease and normal CT angiography findings: a case report

Introduction: Symmetrical peripheral gangrene (SPG) is a rare syndrome characterized by distal ischemic necrosis affecting two or more extremities in the absence of major arterial occlusion or vasculitis. Malaria is an uncommon but recognized trigger, most often described in asso...

Passive sampling reveals composition of airborne bacteria and fungi across five East African cities

Airborne microbes significantly influence environmental processes and human exposure, yet they remain poorly characterized in Africa. This study presents a regional survey of airborne bacterial and fungal communities across 10 sites in five East African countries: Burundi, the De...

GIS-Based Flood Susceptibility Assessment Using the Analytical Hierarchy Process: A Case Study of the Sebeya Catchment, Rwanda

Flood susceptibility mapping is crucial for understanding flood-prone areas and mitigating the associated risks in vulnerable regions like the Sebeya Catchment. This study adopted a GIS-based Analytical Hierarchy Process (GIS-AHP) integrated with local community knowledge to eval...