University of Jeddah

Fabrication of Ag-La-based/Arabic gum nanocomposites via Nigella sativa : Structural, biological activity, and silver release assessment

Ag-La hybrid and Arabic gum-stabilized Ag-La nanocomposites were prepared by a green chemistry method, where an aqueous solution of Nigella sativa seeds was used as a reducing and stabilizing agent. During the synthesis process, silver ions were reduced to Ag 0 , while a fraction...

Burden of CNS neoplasms in the Middle East and North Africa from 1990 to 2023, with projections to 2050

Central nervous system (CNS) neoplasms are uncommon but highly consequential malignancies that account for substantial neurological disability and premature mortality. The Middle East and North Africa (MENA) region is marked by rapid population growth, aging, and uneven health sy...

Thermal-economic performance assessment of heat recovery-oriented design of integrated CCHP-H₂ system; multi-objective optimization with LCA and AdaBoost decision-making

Combined cooling, heating, power systems integrated with hydrogen production (CCHP–H₂) can simultaneously supply useful outputs while improving the utilization of fuel and recoverable thermal energy. The present project proposes a methane-fueled CCHP–H₂ configuration integrating...

Mesenchymal stem cells modulate pancreatic and splenic inflammation through PI3K/AKT/mTOR and TGF-β signalling in diabetic rats

Bone marrow-derived mesenchymal stem cells (MSC) can attenuate diabetic organ damage through immunomodulatory and paracrine mechanisms, yet the specific signalling pathways engaged in the pancreas and spleen remain poorly characterized. This study investigated the effects of a si...

Cell-Free DNA-Based Blood Tests for Colorectal Cancer Screening: Current Advances, Challenges, and Future Perspectives

Background: Colorectal cancer (CRC) is a major cause of rising global rates of cancer-related morbidity and mortality. CRC rates are particularly increasing among younger populations; however, the implementation of effective CRC screening programs remains limited. Colonoscopy, th...

Interfacial synergy in NiO-MnO2-g-C3N4 ternary heterostructure nanostructure for enhanced electrocatalytic water splitting

Developing affordable, highly stable, and efficient bifunctional electrocatalysts for overall water splitting and hydrogen production is essential for advancing clean and sustainable energy technologies. In this study, a ternary heterostructure nanocomposite consisting of NiO, Mn...

Mathematical Analysis of Multi-Route Tuberculosis Transmission with Airborne Environmental Reservoirs and Treatment Failure

Despite the availability of effective treatment, tuberculosis (TB) remains a major public health problem worldwide. Related factors that promote continued transmission include treatment failure, residual infectiousness during treatment, environmental contamination, and progressio...

Addiction management and rehabilitation programs in Saudi Arabia: a scoping review of current practices and opportunities for healthcare technology integration

Substance use disorders (SUDs) represent a growing public health challenge in Saudi Arabia despite strict legal and social controls. Addiction management is primarily delivered through centralized inpatient and residential rehabilitation programs; however, the available evidence...

Catalytic Stereoselective Intermolecular Fluoroacylation of Unactivated Alkynes via C–F Bond Reconstruction

Abstract Herein, we report a transition metal-free synthesis of monofluoroalkenes via a C–F bond reconstruction approach. The process employs inexpensive BF3·Et2O as a catalyst for the stereoselective intermolecular fluoroacylation of unactivated alkynes with alkyl/aryl acid fluo...

Idebenone improves sperm redox balance and embryo fertilization in a mouse model of diet-induced obesity: In vitro fertilization.

Obesity is a significant factor contributing to male subfertility, primarily through mechanisms such as oxidative stress and compromised sperm function. Nevertheless, the efficacy of targeted antioxidant interventions in restoring sperm competence in non-diabetic obesity remains...

A Multi-Agent Framework for Arabic Scam Analysis: Dataset-Specific mT5 Classification and Cultural Annotations

This study presents a multi-agent framework for Arabic scam analysis, with roles for classification, behavioural interpretation and educational guidance. A total of 3000 messages were translated and enriched from English-language collections associated with the Short Message Serv...

Technological and analytical advancements in liquid biopsy for multiomic profiling of lymphomas and immunopathological conditions

This is a review of up to date technological and analytical innovations in liquid biopsy to lymphomas, and its role in multi-omics-based disease characterisation, enhanced diagnostic accuracy, minimal residual disease (MRD) detection and how it can be used to support personalised...

Effect of Artemisia Annua on oxidative stress and antioxidant gene expression in Nile tilapia after chlorpyrifos toxicity

Abstract In this study, the toxic effects of chlorpyrifos (CPF) on fish antioxidant enzyme activity in serum and transcriptomic levels of oxidative stress-related genes in liver tissue and histopathology of the liver tissue of Nile tilapia were examined. Additionally, the effects...

Potentially inappropriate medication use and selected drug-related problems among older adults in Aseer Region, Saudi Arabia: a retrospective multicenter study

Older adults are at increased risk of medication-related safety concerns due to multimorbidity and polypharmacy. Potentially inappropriate medications (PIMs) and drug-related problems (DRPs) are important contributors to medication safety concerns in this population, yet hospital...

A New Iterative Method for Generalized Nonexpansive Mappings

ABSTRACT In this article, we introduce a novel iterative algorithm, called the KK iteration scheme, for approximating fixed points of generalized ‐nonexpansive mappings in Banach spaces. Weak and strong convergence theorems are established in uniformly convex Banach spaces (UCBSs...

Norepinephrine Versus Vasopressin as First-Line Vasopressor Therapy in Septic Shock: Implications for Patients Presenting to the Emergency Department

Background: Septic shock requires rapid restoration of perfusion with infection treatment. Norepinephrine is the recommended initial vasopressor, while vasopressin offers an alternative mechanism of vascular support. This review examines comparative clinical outcomes and their re...

Integrative Multi-Omics Analysis Reveals Host Regulatory and Immune Networks with Inferred Dysbiosis Relevance in Colorectal Cancer

Background: Colorectal cancer (CRC) remains one of the leading causes of cancer-related mortality worldwide. Increasing evidence suggests that intestinal microbial dysbiosis contributes to colorectal tumorigenesis by reshaping host molecular signaling and the tumor immune microen...

Investigation of occupational radiation exposure among students in clinical training and internships using optically stimulated luminescence dosimetry

Background Radiation dose monitoring is essential for undergraduate students who receive clinical training during their bachelor's studies and in clinical practice during their internship, as it underlines the challenges related to radiation protection and helps maintain the safe...

Cadmium and bismuth dopants’ synergistic effect on the photocatalytic dye degradation potential of ZnO/CdO

Currently, several dyes are used in day-to-day activities, and their toxicity poses significant challenges to human health. In this study, the high negative conduction and positive valence band edge of zinc oxide (ZnO) were modified through the inclusion of Cd and Bi dopants as l...

Comparative efficacy and safety of intra-articular versus intravenous tranexamic acid in primary total knee arthroplasty: a systematic review and meta-analysis

Total knee arthroplasty (TKA) is frequently associated with considerable perioperative and postoperative blood loss, making tranexamic acid (TXA) a key component of modern blood-sparing protocols. Although both intravenous (IV) and intra-articular (IA) routes are widely used, the...