University of Ioannina

Prediagnostic circulating 25-hydroxyvitamin D and prostate cancer-specific survival: a collaborative pooled analysis of 13 prospective studies

Abstract Background Previous research suggests higher risk of prostate cancer diagnosis in men with high vitamin D serology, but there are limited data related to prostate cancer survival. In this study, we examine the associations between prediagnostic circulating levels of 25-h...

BMAL1-Mediated Circadian Regulation of Oocyte Quality and IVF Outcomes

Successful embryo development transpires far before fertilization inside the meticulously regulated microenvironment of the ovarian follicle. Increasing data indicates that circadian regulatory systems influence several processes that define oocyte competence, including mitochond...

Sufficiency values through commoning relationality: Exploring a network of community initiatives in northern Greece

In the face of ever-accelerating climate change and ecological degradation, the concept of sufficiency has been proposed as a way to achieve socio-ecological sustainability. Sufficiency implies limits on consumption and production, thus making it incompatible with capitalism’s no...

Climate Change Impacts on One Health Systems: A Narrative Review of Empirical Evidence and Policy Responses

ABSTRACT Background Climate change poses critical threats to human, animal, and environmental health, yet evidence on integrated One Health responses remains fragmented. Although numerous studies highlight climate‐driven health risks, many climate adaptation frameworks still unde...

Enhancing iNKT cell immunotherapy through the integration of optimized CAR endodomains and iNKT engagers

Abstract iNKT cells are emerging as a highly promising immunotherapy platform for the treatment of cancer. To maximise the anti-cancer activity of CAR-iNKT against the blood cancer multiple myeloma we investigated optimal CAR designs and their combination with new iNKT-specific e...

Neurogenic bladder in the multiple sclerosis population: A systematic review and meta-analysis of prevalence and a proposed evaluation algorithm

BACKGROUND: Neurogenic bladder (NGB) is one of the most common and debilitating manifestations of multiple sclerosis (MS), substantially impairing quality of life and increasing the risk of secondary complications. OBJECTIVE: To determine the pooled prevalence of NGB and its subt...

Vitamin–Metal Synergy: Folic-Acid-Based Carbon Nanoassemblies for Optimized Plant Growth

Abstract Developing sustainable strategies to enhance crop yields is critical to meeting global food demands under intensifying climate stress. This study investigates the synthesis and application of folic-acid-based carbon nanoassemblies (FA-CNAs) that integrate magnesium (Mg)...

Energy-Aware Scheduling and Beamforming for Simultaneous Wireless Information and Power Transfer in Low-Earth-Orbit Satellite and UAV Networks Using Lyapunov Optimization, Successive Convex Approximation, and WMMSE

The integration of low-Earth-orbit (LEO) satellites with unmanned aerial vehicles (UAVs) promises high-throughput and flexible wireless connectivity, yet it faces critical challenges in simultaneously guaranteeing data rates and long-term energy harvesting under mobility and impe...

Multimodal Correlates of Longitudinal Functional Decline in Behavioral Variant Frontotemporal Dementia (bvFTD)

Background and Objectives: Functional decline is a major determinant of disability, caregiver burden, and loss of independence in behavioral variant frontotemporal dementia (bvFTD). Although bvFTD is characterized by early and rapidly progressive deterioration in everyday functio...

Assessment of Trophoblast cell surface antigen 2 (Trop-2) expression and its clinical significance in breast cancer: a multi-level analysis of protein and gene expression

Abstract Background Trophoblast cell surface antigen 2 (Trop-2) is a targetable transmembrane glycoprotein commonly overexpressed in breast cancer (BC). This study combines a systematic review and meta-analysis with a retrospective analysis of an independent early BC patient coho...