University of Genoa

Salivary Dim‐Light Melatonin Onset is Associated with Functional Decline, Respiratory Symptom Emergence, and Survival in Early Amyotrophic Lateral Sclerosis

OBJECTIVE: Sleep-wake and circadian disturbances are increasingly recognized in people living with amyotrophic lateral sclerosis (plwALS), but endogenous circadian phase timing and its prognostic significance in early disease remain unclear. We assessed whether salivary dim-light...

Effect of lumbar strengthening exercises on kinesiophobia in people with chronic low back pain: a systematic review

Kinesiophobia is a key psychological factor in CLBP and represents a significant barrier to functional recovery. Strength exercises are commonly recommended for CLBP, yet their specific impact on kinesiophobia remains unknown. A systematic review was conducted to evaluate the eff...

PROOF-THEORETIC RELATIONS BETWEEN HIGMAN’S AND KRUSKAL’S THEOREM, AND INDEPENDENCE RESULTS FOR TREE-LIKE STRUCTURES

Abstract Higman’s lemma and Kruskal’s theorem are two of the most celebrated results in the theory of well quasi-orders. In his seminal paper G. Higman obtained what is known as Higman’s lemma as a corollary of a more general theorem, dubbed here as Higman’s theorem. While the le...

The One Health Action Plan Against Antimicrobial Resistance

Antimicrobial resistance (AMR) represents a severe problem in public health due to the increasing spread amongst the general population, animals, and the environment of antibiotic-resistant microorganisms with resistance phenotypes extended to more than one class of antibiotics [...

Finite elasticity and evolving discontinuities in soft tissues using peridynamic states

Abstract A correspondence model for use with peridynamic states is presented, tailored to the description of finite elasticity in soft tissues within a plane-strain setting. A deviatoric–volumetric energy split leads to a stable one-field correspondence formulation, based on sphe...

Managing growth and puberty concerns in individuals with Duchenne muscular dystrophy: Updated guidance and future directions

Long-term glucocorticoid therapy is standard of care for individuals with Duchenne muscular dystrophy (DMD) but often results in impaired growth and delayed or incomplete puberty, impacting their physical and psychosocial health. Although DMD endocrine care has evolved, leading t...

Exploring the Val Trebbia Defence Committee – Mobilising against damming in 1980s Italy: A chapter in the water war between Genoa and Piacenza over the waters of the Trebbia

This article examines the Val Trebbia Defence Committee, a grassroots initiative formed by local communities in the Trebbia valley in the Northern Apennines of Italy, and focuses on its first campaigns against dam and water diversion projects in 1984. It explores how competing cl...

Microplastics and the Kidney: A Narrative Review of Human Evidence, Molecular Mechanisms of Cell Injury, and Future Directions

Microplastics (MPs) are widespread environmental contaminants, but their potential effects on kidney health remain poorly defined. As an organ continuously exposed to circulating particles and involved in their urinary elimination, the kidney may represent both a target of MP tox...

Impact of Primary Health Care Reforms in Quebec’s Health Care System: A Systematic Review

Introduction: Primary health care (PHC) reforms in Quebec between 2000 and 2023 aimed to improve accessibility, continuity, efficiency, and equity through organisational transformation, notably the Family Medicine Groups (FMGs), centralised waiting lists (Guichets d’accès), the a...

Advances and projects of immunomodulatory biomaterials used for immunotherapy

Abstract Immunotherapy is employed to manage systemic hyperactivation or hypoactivation for the treatment of various diseases. Biomaterial-based immunotherapy systems have the potential to enhance therapeutic outcomes through mechanisms such as targeted drug delivery and immuno-e...

Travel distance to tertiary healthcare reflects disease severity and medication access in Italian systemic sclerosis patients: a geographical study on adult-onset rare diseases from SPRING-SIR registry

Systemic sclerosis (SSc) is a rare, multiorgan disease in adults that requires specialized care. Commuting to tertiary medical centers poses a considerable burden and incurs significant costs, potentially affecting management choices. This study aims to describe the healthcare co...

Incorporating Advanced New or Recycled Materials in Reinforced Concrete Structures

Reinforced concrete continues to be one of the most widely used structural materials worldwide because of its versatility, availability, durability, and ability to accommodate a range of structural forms and loading conditions [...]

Methodology for Modeling and Seismic Analysis of Four Buildings Representative of Bagan’s Monumental Heritage

This paper presents a comprehensive methodology for assessing the seismic vulnerability of four historic monuments in Bagan, including analysis of their architectural and structural characteristics, an evaluation of their behavior in past earthquakes, and finally finite element (...

Netnography in accounting and accountability research: methodological application and future directions

Purpose This study reviews the use of netnography as a methodological approach within accounting and accountability research, focusing on how the method is operationalised in empirical studies. While netnography has gained increasing visibility in the field, limited attention has...

Impact of blood pressure variability on mortality risk of patients with ANCA-associated vasculitis

Abstract Objectives Antineutrophil cytoplasmic antibody–associated vasculitis (AAV) is associated with increased cardiovascular risk, related to persistent inflammation and endothelial dysfunction. Long -term systolic BP variability (SBPV), reflecting vascular damage, may predict...

Acculturation Processes and Food Neophobia

Food is a pivotal agent in the exchange of culture and the evolution of novel dietary practices, exerting influence on both immigrant communities and the host territories. Nevertheless, the process of acculturation frequently engenders tensions within migrant households, impactin...

α- and β-Pinene as a Solvent for Metal Halide Nanocrystal Synthesis

Abstract The hot-injection method is widely employed for the synthesis of high-quality nanocrystals, offering fine control over critical parameters that determine their morphology and properties. However, its major drawback lies in the large volume of waste generated, primarily f...

Challenges of parliamentary engagement in health policymaking in Iran: a qualitative study using Gaventa’s power cube framework

Parliaments play an important role in health governance through legislation, budgeting and oversight. However, their practical influence on health policy decisions remains poorly understood in systems where executive institutions and expert actors dominate policy processes. In Ir...

Capturing the Patient Voice: Qualitative Assessment of Daridorexant’s Impact on Patients with Insomnia and Comorbid Nocturia from a Randomized, Placebo-Controlled Crossover Trial

Chronic insomnia frequently co-exists with nocturia, contributing to impaired sleep quality and reduced health-related quality of life. A recent randomized cross‑over study found that daridorexant improved sleep duration, insomnia severity, daytime functioning, and nocturnal void...

Everything you always wanted to know about sleep, but you were afraid to ask: expert concise guide and recommendations on assessing sleep-wake disturbances within a psychiatric context in contemporary times

OBJECTIVE: While disrupted sleep has long been linked to mental disorders there has been a notable decrease in interest and sleep-wake disorders have received low priority in psychiatric care. The aim of the paper was to present a concise guide for evaluating common sleep-wake di...