University of Duisburg-Essen

Hydrogen-Enhanced Cavitation Erosion Resistance of 316L Stainless Steel

It has been established that hydrogen diffusion can significantly influence the mechanical response of metallic materials under various loading conditions. This phenomenon is particularly evident in reducing the ability for macroscopic plastic deformation. The formation and colla...

Exploring work stressors and resources and their perceived effects on symptoms and work ability in employees with multiple sclerosis: a qualitative study

Abstract Background Adverse working conditions can lead to reduced working hours, career changes, or early exit from the workforce among employees with multiple sclerosis. The aim of the present study was to explore work-related stressors and resources, as well as their effects o...

Multimodal imaging reveals no evidence for magnetite-based magnetoreceptors in the mole-rat eye

Magnetoreception is widespread across animals, but its sensory mechanism remains unresolved. One leading hypothesis proposes that single-domain magnetite is coupled to mechanosensitive ion channels. In subterranean Ansell's mole-rats, such receptors have been proposed to reside i...

Molecular kinetics of protein unfolding at the air/water interface probed by vibrational sum-frequency spectroscopy

Protein behavior at aqueous interfaces is central to many soft-matter, biological, and technological systems, yet the molecular events underlying adsorption-induced structural change remain difficult to isolate. In particular, macroscopic measurements such as surface tension cann...

Interferon-γ-response to mycobacterial glycopeptidolipids in patients with pulmonary non-tuberculous mycobacterial infection

Abstract The understanding of host responses to pulmonary infection with non-tuberculous mycobacteria (NTM) is incomplete and immunodiagnostic tools are not established. Unlike mycobacteria of the Mycobacterium tuberculosis complex, several NTM express glycopeptidolipids (GPLs) i...

When transparency falls short: auditing platform moderation during a high-stakes election

Abstract During major political events, social media platforms encounter increased systemic risks. However, it is still unclear if and how they adjust their moderation practices in response. The Digital Services Act Transparency Database provides—for the first time—an opportunity...

Investigating the Effects of Different Levels of User Control in an Interactive Educational Recommender System

Educational recommender systems (ERSs) are becoming increasingly important in enhancing educational outcomes and personalizing learning experiences by providing recommendations of personalized resources and activities to learners, tailored to their individual learning needs. Whil...

Proteogenomic Analysis of HDAC4 and HDAC5 in Uveal Melanoma

Abstract Uveal melanoma (UM) is a rare but aggressive cancer arising from cells of the uveal tract that is highly resistant to therapy once it has metastasized. In drug screening experiments, we identified a high sensitivity of primary UM cell lines to the pan-histone deacetylase...

Parental needs and experiences with e-Health applications in chronic pediatric care – a scoping review

Abstract Background The number of children and adolescents living with a chronic condition is steadily increasing. These conditions often place a considerable burden on affected individuals and their families. E-Health applications have the potential to support families by provid...

Anomalous Sub‐Band Gap Emission at Room Temperature in Mixed‐Dimensional WS 2 /Cu 2 O Heterostructures

ABSTRACT Practical implementation of two‐dimensional (2D) transition‐metal dichalcogenides (TMDCs) in novel optoelectronics requires a fundamental understanding of carrier dynamics and interfacial states at 2D/3D heterostructures. Herein, a mixed‐dimensional p‐n junction based on...

Linoleic Acid Enhances Murine Natural Killer Cell Function In Vitro but Compromises Mitochondrial Bioenergetic Function During Retroviral Infection

ABSTRACT Natural killer (NK) cells are innate immune cells that eliminate virus‐infected and tumour cells by a plethora of signalling pathways, involving the production of cytokines and cytotoxic molecules. NK cell activation and functions demand substantial energy and fatty acid...

Psychotherapy remission prediction models show limited cross-clinic generalizability in routine outpatient care

Abstract Clinical prediction models for psychotherapy outcomes have the potential to assist therapists in planning a patient’s individual treatment, but their clinical utility depends on maintaining predictive performance across settings. We assessed prediction of post-treatment...

Glaciers and low-DOC ecosystems as sites of microbial carbon production and consumption

Abstract Glacier-fed waters are commonly viewed as heterotrophic ecosystems fuelled by highly bioavailable dissolved organic carbon (DOC), yet this paradigm is largely based on melt-season observations and assumes that microbial DOC dynamics are dominated by consumption. We show...

Structural performance of cement paste cylinders cured in microgravity on the ISS: effects of air-entraining agent and simulated microgravity conditions

Abstract As humanity looks to the stars for future colonies, mastering the science of construction in space begins with a deep understanding of how materials perform in extraterrestrial environment. This study pioneers investigations of microgravity effects on cement paste bulk p...

Sensor-based measurement of fear avoidance and movement patterns of healthy individuals with mechanically induced lower back pain during movement tasks: Study protocol for an experimental non-interventional study

Background Chronic primary low back pain (CPLBP) is highly prevalent and associated with physical impairment and psychological distress. Fear avoidance (FA) is one contributing factor in the development and persistence of CPLBP. Previous studies proved existing connections betwee...

Rules for Using AI with Research Data: Lessons Learned at the FDZ Bildung

The presentation held at the Workshop “AI for Handling (Sensitive) Data in Research Data Centre Contexts: Risks, Mitigation, Training Requirements” on September 14th at GESIS in Cologne. Included are also drafts of the AI Policy in German and ENglish. The English version was tran...

Parvovirus B19 infections in paediatric sickle cell disease patients: Genotype and hydroxyurea treatment influence disease severity

Summary In patients with sickle cell disease (SCD), parvovirus B19 infection (B19V) leads to acute anaemia (aplastic crisis), but may also be associated with other serious complications. We retrospectively analysed clinical data from paediatric SCD patients with B19V infections b...

Gas Chromatography-Ion Mobility Spectrometry for Characterizing Different Species of Origanum and Detecting Blends of Its Products

Abstract Origanum spp. are aromatic herbs with leaves rich in essential oils. The dried leaves of some species are known as oregano and are widely used as culinary herbs. This study evaluates headspace gas chromatography-ion mobility spectrometry (HS-GC-IMS) for profiling the vol...

Why Metrics Matter in Thyroid Eye Disease

Importance Advances in the understanding of the pathophysiology of thyroid eye disease (TED) provide an opportunity to use novel, targeted therapeutic agents. However, our capacity to assess the efficacy and indications for the new agents is potentially limited by the clinical me...

Beyond the developmental state: Exploring the variety of development models in East Asia

East Asia exhibits remarkable economic heterogeneity, yet debates on the region’s development have centered predominantly on the most successful cases, such as Japan, South Korea, and Taiwan, all examples of the so-called “developmental state” model, or China’s economic upswing....