University of Coimbra

Pasture Management and Mineral Fertilization on Soil Properties, Plant Nutrition, and Biomass Production of Urochloa decumbens in Tropical Lixisols

Pasture management and mineral fertilization are key factors influencing soil fertility and pasture yield. However, their effects on the soil properties of Lixisols in the Brazilian semi-arid region, and their subsequent impact on Urochloa decumbens biomass production, remain unc...

Mycoremediation a promising strategy to challenge chemical food hazards

With the fast growth of industrialization, intensive farming, and urban development, environmental pollution has evolved into a major global challenge. The poor handling, bad control, or inadequate management of waste and effluents from households, industries, and agricultural fi...

Antimicrobial Resistance to WHO-Categorised Critically Important Antimicrobials in Piglet-Derived Escherichia coli and Enterococci: A One Health Approach

Antimicrobial resistance (AMR) is a critical health issue affected by human, animal, and environmental factors within a One Health framework. Livestock production, particularly pig farming, contributes to the emergence and spread of resistant bacteria through antimicrobial use an...

Teachers’ mindsets on sustainability: challenges and prospects

Purpose Education is a crucial pillar of social transformation in the pursuit of sustainable development, particularly within higher education. Regarding the central role of teachers, this study aims to critically analyse evidence regarding higher education teachers’ mindsets on...

Polysaccharide Reengineering: Strategic Modifications and Biofunctional Outcomes of Natural Polysaccharides

Natural polysaccharides have attracted considerable interest in pharmaceutical and biomedical applications. However, native polysaccharides often possess limitations, like poor solubility, inadequate mechanical strength, limited stability, and insufficient control over their func...

From mandatory disclosure data to organisational decision-making guided by planetary boundaries

Organisations currently lack operational methods to assess how their activities contribute to returning society to within Earth's safe operating space, considering that seven of the nine planetary boundaries are currently exceeded. Although the mandatory Corporate Sustainability...

FoMOs-A Validation

Abstract: The Fear of Missing Out (FoMO) has become central to understanding adolescents’ engagement with social media and its psychological consequences. Given adolescents’ heightened sensitivity to peer belonging and approval, this study validated the Fear of Missing Out Scale...

New Δ246p53 isoform responds to DNA damage to enhance p53 family functions in cellular senescence

Abstract p53 is, without a doubt, one of the most powerful genes in our genome, as it makes growth vs arrest, repair vs replacement, catabolism vs anabolism, life vs death decisions in the cell. An alteration or malfunction in p53 may lead to cancer, degeneration or premature age...

Bridging skills gaps: how micro-credentials reshape sustainable development learning in higher education

Abstract Micro-credentials (MCs) are gaining traction in higher education as essential tools for advancing sustainable development (SD). These short, focused courses provide learners with specific skills and knowledge related to sustainability, enabling them to address pressing g...

A placebo-controlled randomized cross-over lovastatin trial in neurofibromatosis type 1 reveals Ras/MAPK modulation of dynamic emotional face processing

Abstract Neurofibromatosis type 1 (NF1) is a neurodevelopmental disorder characterized by cognitive and socioemotional processing deficits, associated with dysregulation of the Ras/MAPK pathway and alterations in neural inhibition and the GABA system. This study examined the effe...

A Journey through Solvent Space: New Solvates of Probucol

Abstract A systematic expansion of the solid-form landscape of the antihyperlipidemic drug probucol was carried out using a diverse set of solvents spanning a broad physicochemical space, providing insight into the formation of probucol solvated forms. Five new solvates were disc...

Persistent Post-Burn Pruritus Following Antihistamine Initiation: A Retrospective Longitudinal Study at a Single Italian Pediatric Burn Center

Background/Objectives: An operationally defined unchanged itch-score sequence may indicate persistent symptoms rather than symptom resolution. We described pruritus following antihistamine initiation in children with burns and examined how its apparent stabilization depended on t...

Marine Macroalgae as Sustainable Biofilters: Linking Nitrogen Removal Efficiency with Photosynthetic Performance and Biomass Valorization

Nitrogen pollution and eutrophication are among the most significant environmental challenges affecting coastal ecosystems worldwide, stimulating interest in sustainable nutrient-removal strategies. Marine macroalgae have emerged as promising biological tools for nutrient biofilt...

Hope-Oriented Care in Palliative Care: Relational and Organizational Perspectives From Nurses

Objectives Hope is a dynamic, relational dimension of palliative care; little is known about how nurses themselves perceive and navigate hope-oriented practice. This study aimed to explore experienced palliative care nurses’ perceptions of the relational and organizational barrie...

Building an analysis-ready geospatial dataset for Convolutional Neural Networks-based rural property valuation using LiDAR 3D point clouds

In Portugal, fiscal valuation of rural properties is currently based on the agricultural income obtained in the previous year, disregarding both the productive potential of the land and its market value. To address this limitation, we propose a framework in which rural property v...

Environmental DNA for detecting marine fish species: testing the volume of sampled water, markers and primers in a public oceanarium

To maximize the efficiency of marine fish detection using environmental DNA (eDNA) metabarcoding, methodological factors such as PCR amplification bias and sampled water volume must be carefully considered. In this study, we evaluated the influence of different genetic markers (C...

Torah Epistemology

Torah epistemology refers to the theory of knowledge that emerges from the Hebrew Bible, Rabbinic Judaism, and subsequent Jewish intellectual traditions. Unlike many Western epistemological systems that emphasize abstract rationality, empirical observation, or skepticism as prima...

Structural, thermal, mechanical and physical performance of cellulose fibers based low-density polyethylene/recycled polyethylene terephthalate blend composites

Abstract Despite the increasing interest in recycled polymer composites and natural fiber reinforcement, relatively few studies have systematically examined low-density polyethylene (LDPE)/recycled polyethylene terephthalate (r-PET) blend systems reinforced with cellulose fibers...

Left-right asymmetry in the breast TME is associated with distinct bioelectric and epigenetic tumor features

Breast cancer heterogeneity is shaped not only by intrinsic tumor properties but by the surrounding microenvironment (TME). Here we report a left–right (L–R) asymmetry in the breast TME associated to tumor features. Bioinformatic analysis of TCGA RNA-seq and histological data rev...

Complete Reporting for Transparent Reproducibility Efforts (CORTRE)

The CORTRE project develops a consensus-based reporting guideline for reproduciblity efforts -- projects that systematically re-examine previously published findings to investigate an aspect of their reproducibility. The project was launched at the Responsible Research in Action...