University of Chinese Academy of Sciences

Balanced ElectronDonation Governs Adsorption SiteSelection in CO2 Electroreduction to HCOOH on TransitionMetal-Doped Magnesium Oxides

Abstract Magnesium oxide (MgO) is attractive for CO2 utilization, because interaction with O2. However, the electronic inertness has limited its application in electrochemical catalysis. Herein, spin-polarized dDFT calculations with the BEEF-vdW functional were performed to evalu...

Benchmarking RNA-seq with the Quartet and MAQC reference materials to establish best practices for accurate alternative splicing analysis

Previous limited characterization of short-read RNA-seq (srRNA-seq) accuracy in alternative splicing (AS) analysis due to methodological diversity and lack of reference standards, has left unclear how to achieve optimal performance—an issue increasingly critical with the rise of...

Unraveling theEvolutionary Pathways of Major Productsfrom the Thermal Conversion of 5-Hydroxymethylfurfural

Abstract Thermosensitive 5-hydroxymethylfurfural (HMF) serves as a bridge between biochemical and petrochemical industries, and research into its thermal conversion inherent characteristics is crucial for the preparation of HMF and its derivatives. This study systematically analy...

SmartphoneImaging-Based Luminol Electrochemiluminescenceat the Cobalt Electrode for Sinapic Acid Determination

Abstract Developing simple and portable luminol electrochemiluminescence (ECL) systems without externally added co-reactants is important for on-site analysis. Cobalt is a low-cost and redox-active transition metal with favorable electrocatalytic properties toward water-oxidation...

PrismaticNa-Ion Coordination in the Sulfide-ChlorideSolid Electrolyte Enables Fast Na-Ion Transport

Abstract Designing halide solid electrolytes with high ionic conductivity and robust electrochemical stability is crucial for advanced all-solid-state sodium-ion batteries. Currently, most sodium-based halide conductors suffer from the limited ionic conductivity. In this work, we...

A Configurable and Highly Efficient NTT/INTT/PWM Unit for CRYSTALS-Kyber and CRYSTALS-Dilithium

CRYSTALS-Kyber and CRYSTALS-Dilithium are representative lattice-based post-quantum cryptographic schemes, where number theoretic transform (NTT), inverse NTT (INTT), and point-wise multiplication (PWM) dominate polynomial arithmetic. Existing hardware accelerators are typically...

Structural insights into a substrate translocation pathway revealed by the RND efflux pump complex MexJK from Pseudomonas aeruginosa

Resistance–nodulation–cell division (RND) efflux pumps are the major cause of multidrug resistance in Pseudomonas aeruginosa . The inner membrane protein MexK from P. aeruginosa is a narrow-spectrum RND transporter. It assembles with membrane fusion protein MexJ and outer membran...

Micro- and NanobubblesEnhance the Abatement of BiodegradableMicropollutants in Aged Biological Activated Carbon Filters

Abstract It has been demonstrated that the abatement of micropollutants in drinking water by biological activated carbon (BAC) filters with aged media deteriorates due to the decreased porosity and aerobic metabolism in dense biofilm. In this study, micro- and nanobubbles (MNBs)...

Thermally Modulated Microfluidic Fabrication of Phase-Tunable Cs4PbBr6/CsPbBr3 Hybrid Perovskite Nanocrystals for White Light-Emitting Diodes

All inorganic CsPbBr3 perovskite nanocrystals (NCs) exhibit outstanding luminescence for optoelectronics, yet poor environmental stability severely restricts their practical deployment. As a stable derivative phase, Cs4PbBr6 can effectively improve structural stability. Neverthel...

Mitigating Stress‐Induced Nonphotoactive Phase Transition Through Sodium Sulfonate Engineering for Stable and Efficient Perovskite Solar Cells

ABSTRACT Formamidinium lead triiodide (FAPbI 3 ) perovskite solar cells (PSCs) have attracted significant attention due to their outstanding optoelectronic properties. However, their long‐term stability remains limited by lattice strain‐induced transition from the photoactive α‐p...

Ferromagnetic Coupling in Dual‐Atom Nanozymes Enables Spin‐Favorable Catalase‐Like Catalysis for Rheumatoid Arthritis Therapy

ABSTRACT Iron dual‐atom (Fe DA) nanozymes, structurally analogous to natural catalase, exhibit promising catalase‐like (CAT‐like) activity, yet further improving their catalytic performance and elucidating the underlying mechanism remain major challenges. Herein, we developed a c...

Synergies and trade-offs for reaching global biodiversity and climate commitments

The Kunming-Montreal Global Biodiversity Framework strives to expand high-quality protected areas globally, yet faces economic constraints, climate change and human pressures. This requires integrating biological and socio-economic complexity while ensuring equity. We explore mul...

Endowing CentrosymmetricOxides with Effective Piezoelectricityvia Oxygen Vacancy Engineering and Single-Atom Anchoring for MulticatalyticSono-Immunotherapy

Abstract Due to piezopotential-driven energy band tilting and the promotion of charge carrier separation, sonopiezoelectric therapy (SPT) holds promise in overcoming the limitations of band structure. However, the dependence of the piezoelectric effect on noncentrosymmetric cryst...

Orbital Engineering via Double‐Exchange Interaction in a Bimetallic MOF for Electrocatalytic C─S Coupling of CO 2 and Sulfate

ABSTRACT Guided by molecular orbital theory, we have designed and synthesized a novel bimetallic metal‐organic framework (BTC‐Co‐O‐Cu‐BTA) for the electrocatalytic C─S coupling of CO 2 and sulfate. The integration of edge/corner‐sharing CoO 6 octahedra and CuO 5 square pyramids e...

Rhodium-Catalyzed C–H Functionalization Enabling Divergent Heterocycle Syntheses

Abstract Direct C–H bond functionalization represents a facile synthetic strategy that adheres to the principle of atom economy. Among a variety of metal catalysts, rhodium catalysts demonstrate distinctive advantages owing to their excellent reactivity. This account summarizes o...

Nanoconfinement Engineering Enables Pt Nanocrystals in MOF-on-MOF Derived Nanoporous Carbon Microspheres for Hydrogen Evolution

Abstract Developing Pt-based catalysts with maximized atomic utilization and optimized electronic structures remains crucial for accelerating the cathodic hydrogen evolution reaction (HER). Herein, we develop a MOF-on-MOF-derived confinement strategy to construct a defect-mediate...

Skeletal muscle H3K18 lactylation inhibits hepatic gluconeogenesis through IL-6 mediated interorgan communication

The mechanisms underlying the dynamic interplay between skeletal muscle and systemic glucose homeostasis in type 2 diabetes remain elusive. Increased lactate level has long been noticed in diabetes, however, whether the elevated lactate is a cause or consequence of impaired gluco...

Symbolic or Substantive? The Impact of Managerial Climate Awareness on Firms' Sustainability

ABSTRACT This study examines whether managerial climate awareness contributes to symbolic or substantive sustainability of Chinese publicly listed firms. We find that only when managers' climate awareness is high enough will they significantly drive firms toward substantive susta...

A Study on the Distribution Characteristics of Salinity and Nutrients and the Migration Mechanism of Soil Salt in the Delingha Saline‐Alkali Soil Profile of the Qaidam Basin

ABSTRACT Soil salinization negatively impacts the economic development and ecological environment, particularly in the arid and semiarid regions of China. The Qaidam Basin constitutes a major distribution area of saline‐alkali land in the country. However, the distribution patter...

Manganese Ion‐Based NanoPlatforms for Tumor Theranostics

ABSTRACT Manganese‐ion‐based nanoparticles have emerged as highly versatile platforms that seamlessly integrate diagnostic and therapeutic functions, enabling precision cancer theranostics. In this review, we discuss manganese‐based nanomaterials through a design‐oriented framewo...