University of Chester

Retinoic Acid Receptor γ Is a Ligand-Activated Gatekeeper to Stem Cell Developmental Progression

RARγ is expressed during embryogenesis by stem/primitive progenitor cells, indicating a role in controlling their development. Supporting this view is that a physiological level of 10 nM of the RARγ agonist AGN205327 blocked stem/progenitor cell differentiation during zebrafish e...

Patient involvement with the HCR-20: a qualitative interview study of professionals’ experiences of collaborative risk assessment and management

Purpose The assessment and management of violence risk is integral to a patient’s care pathway in secure mental health care. Risk assessment tools, such as the Historical Clinical Risk-20 (HCR-20), are embedded in practice, framing an individual’s risk and supporting clinical dec...