University of Cape Town

Effectiveness of tuberculosis treatment in individuals exposed to silica or with silicosis: a systematic review and meta-analysis

Tuberculosis (TB) is a global problem affecting large numbers of workers exposed to respirable crystalline silica. Both silicosis and exposure to silica without silicosis increase the risk of active TB. While some studies have suggested that silicotuberculosis (silicosis plus TB)...

A Description and Critique of the Quarterly Labour Force Survey Public Earnings Data: 2010–2023

ABSTRACT In this paper, I summarise research noting concerns with the quality of the QLFS earnings imputations, provide a description of the publicly available QLFS earnings data between 2010 and 2023 and describe how the structure of the earnings data that has been released publ...

Baseline characterization of inshore reef soundscapes and noise dynamics along the southeast coast of South Africa

Underwater noise has risen in certain parts of the world, driven by continued growth of maritime economic activity. In South Africa, increasing economic development threatens to elevate underwater noise levels in marine habitats, yet knowledge of marine soundscapes remains very l...

Cannabidiol selectively downregulates FAM111B expression and induces apoptosis in fibrosarcoma cells: an in vitro study

Abstract Background Fibrosarcoma is a rare and aggressive soft tissue sarcoma with limited therapeutic options and poor outcomes in advanced disease. Family with sequence similarity 111 member B (FAM111B) has emerged as a pro-tumorigenic factor associated with dysregulated cell s...

Drug stock-outs in HIV, tuberculosis, and malaria programs: a systematic review

Background Stock-outs of antiretroviral, anti-tuberculosis, and anti-malarial medicines remain a major challenge in low- and middle-income countries, affecting both health systems and patient outcomes. This systematic review aimed to synthesize evidence on the causes, consequence...

Accumulation of Metals and Metalloids in Marine Invertebrates and Macroalgae in False Bay (Cape Town, South Africa)

The concentrations of 18 metal(loid)s were measured in five marine invertebrate species (Oxystele tigrine and sinensis, Marthasterias glacialis, Cymbula oculus and granatina, Parechinus angulosus, and Mytilus galloprovincialis) and five macroalgae/seaweed species (Aeodes orbitosa...