University of Campania "Luigi Vanvitelli"

Exploring Career Competencies: An Italian Validation Study of the CCQ and Test of Its Nomological Net

Career competencies are widely acknowledged as critical self-regulatory resources for achieving career success. The measurement of career competencies has been largely confined to restricted cultural contexts, limiting theoretical development and practical application. Addressing...

The procrastination trap: How temperament undermines students’ career readiness in Poland

This study examines links between temperament, procrastination tendencies, and self-perceived employability among Polish university students, addressing a notable gap in research on behavioral postponement effects in European higher education contexts. Cross-sectional survey data...

ACTN3 Variants Beyond Performance: Metabolic and Inflammatory Implications

Background: Athletic performance is a result of interaction between genetic and environmental factors, including training, nutrition, rest, hormonal and psychophysiological status. Numerous genes and polymorphisms can influence key physiological processes, such as muscle contract...

Revisiting Inherited Metabolic Diseases ( IMDs ) Through the Lens of Selective Autophagy

ABSTRACT Selective autophagy is increasingly recognized as a fundamental quality‐control mechanism that complements bulk autophagy by enabling the targeted degradation of specific intracellular cargos, including mitochondria, endoplasmic reticulum (ER), lipid droplets, glycogen,...

Medication Complexity and Insomnia Severity in Psychiatric Outpatients: A Moderation Analysis Across Mood and Non-Mood Disorders

Background: Insomnia is common and occurs across psychiatric diagnoses. A prior analysis of this outpatient cohort found that psychotropic medication complexity was associated with insomnia severity, but whether this association is stronger in particular diagnostic groups was not...

Artificial Intelligence-Based Evaluation of Oral Potentially Malignant Disorders Using Photographic and Clinical Data: A Retrospective Exploratory Diagnostic Accuracy Study

Objective: The objective of this study was to evaluate the diagnostic performance of GPT-5.2 Thinking in identifying oral potentially malignant disorders within a patient sample that also included oral carcinomas and other oral cavity lesions, using intraoral photographs and asso...

Impact of GLP-1 Receptor Agonists on Cognitive Performance in Adults at Risk of Alzheimer’s Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Background/Objectives: Type 2 diabetes, a widely recognized risk factor of Alzheimer’s disease (AD), is mainly due to the role played by insulin resistance on neuronal degeneration. Mild Cognitive Impairment (MCI) also significantly increases the risk of developing AD by approxim...

The robotic PIANO: a critical narrative review of surgeon-controlled operative polyphony, human factors, and robotic training

Abstract Robotic surgery can concentrate control of several technical functions at the console, but such concentration does not itself confer clinical independence, reduce dependence on the perioperative team, or improve patient outcomes. We define surgeon-controlled operative po...

Everything you always wanted to know about sleep, but you were afraid to ask: expert concise guide and recommendations on assessing sleep-wake disturbances within a psychiatric context in contemporary times

OBJECTIVE: While disrupted sleep has long been linked to mental disorders there has been a notable decrease in interest and sleep-wake disorders have received low priority in psychiatric care. The aim of the paper was to present a concise guide for evaluating common sleep-wake di...

Computational identification and experimental validation of early glycinergic impairments in spinal muscular atrophy

Spinal Muscular Atrophy (SMA) is a progressive neurodegenerative disorder characterized by lower motor neuron (MN) loss, due to mutations or deletions in the Survival Motor Neuron 1 ( SMN1 ) gene. Increasing evidence implies mitochondrial dysfunctions in SMA, suggesting these org...

Pharmacokinetic/Pharmacodynamic Optimization and Therapeutic Drug Monitoring of Beta-Lactam Antibiotics in Abdominal Sepsis: Current Evidence, Challenges, and Clinical Perspectives—A Narrative Review

Background: Abdominal sepsis is associated with profound pharmacokinetic (PK) alterations that make standard beta-lactam dosing regimens potentially inadequate in critically ill patients. Increased volume of distribution, hypoalbuminemia, augmented renal clearance (ARC), acute ki...

Life‑cycle analysis of bio‑based phase change materials in recycled‑aggregate mortars: sourcing sensitivity and trade‑offs

Abstract The decarbonization of construction materials requires circular design strategies supported by life‑cycle thinking. This study quantifies the cradle‑to‑gate (A1–A3) environmental impacts of three mortar formulations: (i) a Reference mortar, (ii) a mortar incorporating re...

Evidence-based atlas of risk and protective factors for psychotic disorders: an umbrella review to inform personalized prognosis and prevention.

Identifying updated, evidence-based risk and protective factors for psychotic disorders is essential to advancing scientific and clinical knowledge of their etiology. Since the most recent umbrella review published in this journal, the evidence base has expanded substantially. Fo...

The lived experience of trans persons: a bottom-up review co-written by experts by experience and academics.

We present here the first bottom-up review of the lived experience of trans persons, co-written by experts by experience and academics. We sourced the medical and non-medical literature, focusing on first-person narratives, and critically extracted experiential themes, which were...

Abnormal neurovascular coupling in the precuneus–posterior cingulate cortex may bridge simple and complex aura phenomena in the migraine brain

Migraine aura is a heterogeneous phenomenon in which visual symptoms predominate, while a substantial proportion of patients also experience somatosensory and, more rarely, dysphasic or motor manifestations. While neurovascular coupling (NVC) abnormalities within the visual corti...

The Italian Version of the Lesbian, Gay, Bisexual and Transgender Development of Clinical Skills Scale (LGBT-DOCSS): Validation Among Mental Health Professionals

INTRODUCTION: Sexual and gender minority (SGM) individuals experience substantial health inequalities, and clinical competence among healthcare providers is a key determinant of equitable care. The Lesbian, Gay, Bisexual and Transgender Development of Clinical Skills Scale (LGBT-...

Aerodynamic shape optimisation of distributed propulsion using a meshless computational approach

Abstract A surrogate-assisted framework for the aerodynamic optimisation of distributed propulsion architectures is presented using the reformulated vortex particle method (rVPM) implemented in the open-source FLOWUnsteady solver. The approach targets early-stage design, enabling...

High-fat diet promotes T cell–mediated synaptic dysfunction in multiple sclerosis

Early glutamatergic synaptopathy contributes to disease progression in multiple sclerosis (MS), leading to excitotoxic synaptic damage. Although high-fat diet (HFD)–associated peripheral inflammation has been linked to central nervous system dysfunction, how metabolic and immune...

Biliary-type pain in children with chronic abdominal pain: A cross-sectional, observational study.

OBJECTIVES: Functional gallbladder disorders are well-recognized entities in adults with standardized diagnostic criteria since the Rome III criteria. The existence of these disorders in children is still debated. The primary aim was to estimate the prevalence of disorders of gut...

Functional appliances and airway in class II malocclusion

Abstract Purpose The potential influence of functional appliances on respiratory health has recently gained attention, though evidence remains inconsistent. This umbrella review and meta-analysis evaluated the impact of functional appliances on the upper airway area and volume as...