University of Cagliari

Migraine in Real-World Clinical Practice: Patient Burden, Healthcare Utilization and Unmet Needs—A Cross-Sectional Analysis of the I-GRAINE Study

What are the main findings?Migraine care in Italy is characterized by a mismatch between healthcare resource utilization and clinical needs, with limited primary-care involvement, repeated specialist consultations, and healthcare nomadism.Healthcare resource utilization is substa...

The Italian Version of the Lesbian, Gay, Bisexual and Transgender Development of Clinical Skills Scale (LGBT-DOCSS): Validation Among Mental Health Professionals

INTRODUCTION: Sexual and gender minority (SGM) individuals experience substantial health inequalities, and clinical competence among healthcare providers is a key determinant of equitable care. The Lesbian, Gay, Bisexual and Transgender Development of Clinical Skills Scale (LGBT-...

Associations Between Wake‐Time and Sleep‐Time Masticatory Muscle Activity and Clinical Correlates in Free‐Living Adults

ABSTRACT Aim To investigate associations between wake‐time and sleep‐time masticatory muscle activity (MMA) in free‐living adults with high levels of oral behaviours, and to examine associations with tooth wear, masticatory muscle pain, stress, and anxiety. Methods In this observ...

Tectonic and environmental controls on Upper Triassic–Jurassic carbonate successions of the eastern Northern Calcareous Alps (Stumpfmauer, Austria)

The western Neo-Tethys Austroalpine and Southern Alps sedimentary successions are proven archives of environmental and climatic changes and tectonic activity across the Triassic to Jurassic times. These Upper Triassic–Jurassic, dominantly carbonate, shelf deposits witnessed the e...

The Marine Biomonitor Mytilus galloprovincialis: A Study on Microplastics as a Vector for Heavy Metals Pollution in Sardinia (Italy)

The main objective of the present study was to assess the contamination level and nature of microplastics and their role as vectors of trace elements in Mediterranean mussels (Mytilus galloprovincialis). A total of 39 samples were collected from four farming areas (1–4) located i...

Bioarcheological Insights From Fragmented Remains: Using Dental Health to Understand the Punic Necropolis of Monte Luna

ABSTRACT To investigate oral health in the fragmented human remains from the Punic necropolis of Monte Luna, Sardinia, and evaluate what dental pathologies reveal about lifeways and diet. Human remains from 227 individuals recovered from 70 tombs were analyzed, including 21 femal...

The digitalisation of Italian political parties: a formal analysis of party statutes

This article examines the attention paid to digitalisation by Italian political parties. To this end, using an original methodology, we analyse the statutes adopted between 2008 and 2025 by the 11 parties represented in the Italian Parliament elected in 2022. The analysis assesse...

Construction and characterisation of the DarkSide-20k veto silicon photo-multiplier tiles

Abstract Silicon photo-multipliers (SiPMs) are state-of-the-art sensors capable of detecting a single photoelectron under cryogenic conditions, with potentially lower radioactivity than widely used photomultiplier tubes. The DarkSide-20k experiment, designed to perform direct dar...

The Behavior of the External Limiting Membrane and Ellipsoid Zone in Diabetic Macular Edema: A Population AI-Assisted Optical Coherence Tomography Study

Purpose: To investigate the behavior of the external limiting membrane (ELM) and ellipsoid zone (EZ) in diabetic macular edema (DME) using artificial intelligence (AI)-based optical coherence tomography (OCT) quantification. Methods: This was a cross-sectional study. OCT scans of...

FOXC1 and its lncRNA FOXCUT link DNA methylation to a chondrocyte phenotype dysfunction

Abstract Objective With current osteoarthritis (OA) therapies limited to symptom management, understanding molecular drivers of disease progression is critical. As epigenetic mechanisms increasingly appear central to OA pathogenesis, this study aimed to identify epigenetically dy...

On the effectiveness of memory analysis in revealing maliciousness in android applications

Nowadays, Android malware has gained attention due to its ability to infect widely used mobile devices. Typically, current detection approaches rely on static and dynamic techniques to extract several kinds of features, to learn and identify common malicious patterns. However, mo...

Breeding progress and climate adaptation in semi‑dwarf durum wheat: Genetic gains from long‑term multi‑environment trials under a Mediterranean environment

Durum wheat is a key cereal in Mediterranean agriculture, where productivity is challenged by climate change and yield stagnation. However, information on genetic gains after the introduction of Rht genes remains limited. This study quantified breeding progress and associated tra...

Prognostic Role of Adverse Events in a Worldwide Population of Patients with Biliary Tract Cancer Treated with Chemo-Immunotherapy

Background: Biliary tract cancers (BTCs) are aggressive malignancies with limited treatment options. The addition of durvalumab or pembrolizumab to cisplatin–gemcitabine improves overall survival (OS), but validated biomarkers of benefit remain limited. Immune-mediated adverse ev...

Gastric Mucosa Cancer Risk: The Operative Link on Gastritis Assessment Staging System

Gastric mucosa atrophy is the cancerization field for gastric cancer development. Atrophic changes in the gastric mucosa can be assessed endoscopically and histologically. Gastric serology (e.g., pepsinogens and their ratio, and gastrin) may provide information on the functional...

Predicting the risk of dehydration and readmission among rectal cancer patients with ileostomy: a multicenter observational study

Abstract Dehydration is a frequent complication among rectal cancer patients after ileostomy, often resulting in hospital readmission. The Dehydration Readmission after Ileostomy Prediction (DRIP) score was used to identify patients at risk of dehydration-related readmission. The...

Fair backward compatibility: definitions, theoretical framework, and empirical results

Machine learning systems often require updates for various reasons, ranging from the availability of new data or models to the necessity of meeting new or revised technical and ethical metrics. Typically, such metrics capture average performance rather than sample-wise behavior....

Biovid dataset and challenge: biometric user recognition on smartphone data in real-world conditions

Abstract User authentication is more and more crucial in everyday life, with researchers developing sophisticated, yet easy-to-use, approaches to enforce secure authentication while providing a smooth user experience. This is particularly true in mobile authentication, in which t...

Microbiome and Metabolomics in Obesity: Advances in Understanding and Interventions Across the Lifespan

ABSTRACT Obesity arises from intertwined and reciprocal diet‐microbiome‐host pathways that reshape energy balance, insulin sensitivity, and inflammation. This review synthesizes mechanistic links between microbial functions and metabolic control, charts lifestyle‐related lifecour...

Emotional Reliance on Artificial Intelligence: A Scoping Review of AI Companionship and Mental Health Implications

Background: Artificial intelligence (AI)-driven conversational systems are increasingly capable of simulating empathy, adapting to individual users, and fostering emotional bonds that blur the boundary between tool and companion. This scoping review maps the extent and nature of...

High Hepatitis A Virus Seroprevalence and Low Self-Reported Vaccination Coverage Among Waste Collection Workers in Sardinia, Italy: A Retrospective Cross-Sectional Study

Background/Objectives: Hepatitis A virus (HAV) infection is a relevant biological risk in some occupational settings and has long been discussed as an occupational health concern among municipal waste collection workers. Data on HAV seroprevalence and vaccination history in this...