University of Cagliari

Neanderthal’s heel: How the Neanderthal’s external calcaneal shape uniquely differs from that of modern humans

Neanderthals exhibit unique morphological adaptations in their calcaneus compared to Homo sapiens , shedding light on distinct evolutionary pressures and functional requirements shaping their respective foot anatomy. This study assesses which calcaneal traits represent plesiomorp...

Neural encoding of symbolic, non-symbolic, and embodied non-symbolic numerical information in young and older adults

Numeracy has important implications across the lifespan, and age-related decline in this ability represents a vulnerability factor for older adults in managing everyday tasks, yet its mechanisms remain poorly understood. This study employed a parity judgment task to examine age-r...

Mycobacterium chelonae as an Underrecognized Cause of Granulomatous Disease in Fish and Humans: A Molecular One Health Study

Non-tuberculous mycobacteria are recognized as pathogens affecting aquatic animals and humans. Although Mycobacterium marinum is traditionally considered the principal etiological agent of fish mycobacteriosis and fish-tank granuloma in humans, the contribution of Mycobacterium c...

Diet, Ultra-Processed Foods, and Food Additives in Crohn’s Disease: A Comprehensive Review

Background and aim: Crohn’s disease (CD) is a chronic inflammatory disorder of the gastrointestinal tract resulting from a complex interplay among genetic susceptibility, immune dysregulation, environmental factors, and alterations in the gut microbiota. Among these, diet has eme...

Operational Multi-Source Data Fusion for High-Resolution LULC Mapping

High-resolution and regularly updatable land cover maps are essential for local-scale environmental monitoring, water resource management, and territorial governance, yet existing global and regional products fail to provide the spatial detail and thematic richness required for o...

Benchmarking of multi-order equivalent-circuit models with empirical ageing for Li-ion battery digital-twin workflows

Accurate and computationally efficient battery models are essential for battery management systems and battery digital-twin workflows. However, model selection requires careful evaluation of the trade-off between dynamic voltage fidelity, computational effort, energy accounting,...

Isocitrate dehydrogenase (IDH) as target for anticancer therapy in brain and gastrointestinal cancers

Isocitrate dehydrogenase (IDH) enzyme system plays a central role in cellular metabolism, growth, and differentiation, and its mutations are associated with alterations of the cell cycle and production of oncometabolites, promoting tumor development. In this narrative review, we...

Data-Driven Ensemble Machine Learning for Multi-Horizon Microalgal Bioprocess Forecasting

Microalgal bioprocesses increasingly rely on predictive modelling to support automated control and reduce the cost of laboratory experimentation. Yet, the scarcity of high-quality datasets and the nonlinear nature of microalgal growth severely limit the accuracy and robustness of...

Techno-Economic and Environmental Analysis of an Optimized Hydrogen Refueling Station Integration in a Renewable Energy Microgrid

Fuel cell electric vehicles represent a promising option for reducing greenhouse gas emissions from heavy-duty transport. In this context, integrating Hydrogen Refueling Stations (HRSs) into renewable-based microgrids represents a key strategy for ensuring sustainable hydrogen pr...

Phytochemical characterization and preliminary antimicrobial evaluation of a mono- and sesquiterpene-rich essential oil of Salvia limbata C.A.Mey.

Understanding how chemotype and geographic origin influence essential oil composition and bioactivity is crucial for the identification of new plant-derived antimicrobials. In this study, the essential oil obtained from aerial parts of Salvia limbata C.A.Mey., collected in May 20...