University of Brescia

Finite elasticity and evolving discontinuities in soft tissues using peridynamic states

Abstract A correspondence model for use with peridynamic states is presented, tailored to the description of finite elasticity in soft tissues within a plane-strain setting. A deviatoric–volumetric energy split leads to a stable one-field correspondence formulation, based on sphe...

Microplastics and the Kidney: A Narrative Review of Human Evidence, Molecular Mechanisms of Cell Injury, and Future Directions

Microplastics (MPs) are widespread environmental contaminants, but their potential effects on kidney health remain poorly defined. As an organ continuously exposed to circulating particles and involved in their urinary elimination, the kidney may represent both a target of MP tox...

Virtual element approximation of eigenvalue problems: Is the stabilization of the right hand side necessary?

The VEM approximation of eigenvalue problems usually involves the appropriate tuning of stabilization parameters, unless self-stabilizing or stabilization-free VEM are used. In this paper we prove that for elliptic self-adjoint eigenvalue problems the stabilization of the mass ma...

Organizing healthcare delivery in the era of disease-modifying therapies for Alzheimer’s Disease: an Italian RAND/UCLA consensus

BACKGROUND: Alzheimer's disease (AD) poses a growing clinical and organizational challenge, requiring coordinated, multidisciplinary care models. In Italy, significant regional variability in resources and access to diagnostic services persists, while the implementation of commun...

Posterosuperior and Anterior Rotator Cuff Repairs Yield Comparable 1‐Year Constant Scores in Routine Clinical Practice: A Propensity Score‐Matched Study From LaTour Group

Purpose To compare clinical outcomes and ultrasound‐assessed healing rates between posterosuperior and anterior rotator cuff repairs using propensity score matching. Methods Consecutive patients undergoing rotator cuff repair between 2015 and 2021 by a single fellowship‐trained s...

Travel distance to tertiary healthcare reflects disease severity and medication access in Italian systemic sclerosis patients: a geographical study on adult-onset rare diseases from SPRING-SIR registry

Systemic sclerosis (SSc) is a rare, multiorgan disease in adults that requires specialized care. Commuting to tertiary medical centers poses a considerable burden and incurs significant costs, potentially affecting management choices. This study aims to describe the healthcare co...

Design and Development of an Automated Surface Tension Analyzer Based on Bubble Pressure Variations

A low-cost, automated surface tension analyzer was designed and developed based on the maximum bubble pressure method. The system measures the pressure required to form air bubbles through a capillary immersed in a liquid, allowing the surface tension to be determined from the pr...

Putting the pieces together: A case report on human remains identification driven by tattoo recognition

Dismemberment is a relatively uncommon phenomenon in forensic pathology; its aim is to hinder identification and facilitate corpse concealment. We present a case of fragmented remains where facial recognition was impossible and fingerprints yielded no matches in law enforcement d...

Impact of blood pressure variability on mortality risk of patients with ANCA-associated vasculitis

Abstract Objectives Antineutrophil cytoplasmic antibody–associated vasculitis (AAV) is associated with increased cardiovascular risk, related to persistent inflammation and endothelial dysfunction. Long -term systolic BP variability (SBPV), reflecting vascular damage, may predict...

Gate Electrode Engineering for Tunable Synaptic Plasticity in Organic Electrochemical Neuromorphic Devices

ABSTRACT Organic electrochemical transistors (OECTs) are widely studied for neuromorphic hardware, as their volumetric electrochemical doping couples ionic and electronic transport to mimic biological synaptic transmission. Research on OECT‐based artificial synapses has focused p...

Overwhelming post-splenectomy Capnocytophaga canimorsus infection complicated by suspected infection-associated secondary thrombotic microangiopathy with a complement-mediated hemolytic uremic syndrome phenotype and extensive tissue necrosis after a dog bite

Capnocytophaga canimorsus is a rare zoonotic pathogen that can cause fulminant sepsis in asplenic patients, including overwhelming post-splenectomy infection after dog bites. Its association with suspected infection-associated secondary thrombotic microangiopathy with a complemen...

Migraine in Real-World Clinical Practice: Patient Burden, Healthcare Utilization and Unmet Needs—A Cross-Sectional Analysis of the I-GRAINE Study

What are the main findings?Migraine care in Italy is characterized by a mismatch between healthcare resource utilization and clinical needs, with limited primary-care involvement, repeated specialist consultations, and healthcare nomadism.Healthcare resource utilization is substa...

Postpandemic Trends in Pediatric Respiratory Virus Hospitalizations: A Multicenter Study, 2019–2025

ABSTRACT Background The COVID‐19 pandemic profoundly altered the circulation of respiratory viruses in children, changing the epidemiology of acute lower respiratory tract infections. In the postpandemic period, respiratory pathogens showed marked temporal variability. The 2024–2...

Long-Term Assessment of Polychlorinated Dibenzo-p-dioxins and Dibenzofurans (PCDD/Fs) and Polychlorinated Biphenyls (PCBs) in the Ambient Air of Brescia, Northern Italy

From April 2015 through August 2022 levels of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) and polychlorinated biphenyls (PCBs) were measured in ambient air (particulate and gas phases) at an urban site in Brescia, northern Italy. A total of 75 monthly samples (f...

Quantitative framework for synthesising defocus-curve evidence in simultaneous-vision intraocular lenses

Background/aims To develop a quantitative, meta-analytic framework to synthesise defocus-curve evidence and describe functional visual performance of simultaneous vision intraocular lenses (SVIOLs) across clinically relevant visual ranges. Methods PubMed was searched from incepti...

Impacts of climate and land use changes on water retention in the transboundary Yuanjiang-Red River Basin: Historical attribution and future projections

Study region the Yuanjiang–Red River Basin (YRRB), Southeast Asia. Study focus Water retention (W R ) capacity in the transboundary YRRB has been increasingly affected by combined climate and land-use changes. However, limited quantitative attribution of historical drivers and un...

Neoplasms Metastatic to the Larynx: A Systematic Review

Metastatic involvement of the larynx from nonhead and neck primary tumors is an exceptionally rare event, frequently misdiagnosed as a primary laryngeal lesion and at risk of inappropriately aggressive surgical management. This systematic review aimed to define the most common pr...

Radiomics-based prediction of pituitary adenoma consistency: a systematic review and meta-analysis

Abstract Purpose Pituitary adenoma consistency significantly influences surgical strategy and outcomes, yet it cannot be reliably predicted using conventional imaging. By converting images into quantitative data, radiomics can identify imaging patterns that may not be distinguish...

Bioinspired Mechanosensitive Organic Artificial Neuron With Programmable Excitatory and Inhibitory Responses via Nonlinear Mechano‐Electrochemical Coupling

ABSTRACT Neuromorphic systems capable of directly interfacing with the physical world are essential for embodied intelligence, wearable bioelectronics, and adaptive human‐machine interaction. However, most artificial neurons process mechanical and chemical stimuli through externa...

Bearing behavior of additively manufactured Onyx–Kevlar composites: effect of fiber content and mixed distribution

Abstract This study investigates the pin-bearing behaviour of additively manufactured Onyx–Kevlar composites, focusing on the interplay between fiber content and layer-wise distribution. Specimens were fabricated via Continuous Filament Fabrication with longitudinal Kevlar covera...