University of Alicante

Functional Nanostructured Carbon Honeycomb Monoliths for Hemoadsorption: Preliminary Studies on Biocompatibility, Protein-Bound Uremic Toxins and Inflammatory Cytokines Elimination

Rice husk (RH) is a renewable siliceous lignocellulosic waste providing a unique, greener and less toxic alternative to conventional synthetic polymeric precursors in the production of carbon-based materials for biomedical applications. In this work we studied the porous structur...

Organisational fields as knowledge systems: canon path dependence and the organisation of coherence

Purpose This study aims to examine how theoretical coherence is produced and maintained within an organisational field as theoretical diversity expands. It introduces canon path dependence to explain how dominant frameworks may persist through processes of extension without subst...

Beyond [ N ]Phenylenes: Synthesis and Investigation of Linear [4] and [5]Naphthylenes Incorporating Multiple Four‐Membered Rings

ABSTRACT Ladder‐type polycyclic conjugated hydrocarbons (PCHs) incorporating four‐membered rings represent a unique class of organic materials with local antiaromaticity and dearomatization induced by the four‐membered rings. [ N ]Phenylenes represent the only systematically synt...

Rainfall-induced microbial resuscitation reveals functional decoupling across biocrust succession

Abstract Dryland ecosystems rely on infrequent rainfall pulses to activate soil microbial communities, yet the fraction and identity of microbes resuscitating after hydration remain unclear. We applied bioorthogonal non-canonical amino acid tagging coupled with fluorescence-activ...

The art of war is to avoid fighting: an analysis of entry deterrence in the context of an innovation shock

Purpose This study tests the theory of entry deterrence in the context of an innovation shock. Specifically, this article investigates the extent to which within-niche product proliferation implemented by incumbents (firms already established in a submarket), their organizational...

Stakeholder preferences for managing massive fish escapes from aquaculture under increasing extreme coastal events in Spain

Climate change can significantly increase massive fish escapes from marine aquaculture facilities as coastal extreme events become more frequent and severe. Despite the significant environmental and economic consequences of fish escapes, regulations and management measures remain...

Monocular and binocular vision function following patching alone versus combined patching and active vision therapy in non-strabismic refractive amblyopia

Purpose To evaluate binocular visual function in amblyopic patients who achieved optimal visual acuity following treatment with either conventional patching alone or combined patching and structured Active vision therapy (AVT).Methods This retrospective chart review included 67 p...

Clinical outcomes of stereotactic body radiotherapy in oligometastatic disease: a national real-world cohort study

Abstract Purpose We conducted the first multicentre Spanish real-world study assessing the efficacy and safety of stereotactic body radiotherapy (SBRT) in oligometastatic patients treated in routine clinical practice. Methods This retrospective, multicentre observational study in...

Wine tourism and sustainable regional development: A triple bottom line perspective

Wine tourism is increasingly recognized as a driver for value creation in wineries. The main objective of this research is to analyze the economic, social, and environmental effects of wine tourism at the firm and the regional levels. The methodology used is the case study. The f...

Effect of Freeze Concentration on the Process Parameters, Physicochemical Properties, Total Bioactive Compounds and Antioxidant Capacity of Almond Milk

The objective of this study was to evaluate the application of centrifugal block freeze concentration (CBFC) in fresh almond milk to obtain a concentrated liquid sample with enhanced chemical composition, total bioactive compounds (TBC), antioxidant activity, and process paramete...

Low reliability and high redundancy in inter-limb asymmetry: Effects of formula and variable selection

Inter-limb asymmetry monitoring is widely used for athletic performance and injury-risk assessment, yet the longitudinal psychometric impact of formula selection remains poorly understood. This study examined the methodological variability and reliability of ten commonly used int...

Incidence, Causes, and Outcomes of Conversion to Open Surgery During Minimally Invasive Left Pancreatectomy: A Prospective Multicenter Study

ABSTRACT Background Minimally invasive left pancreatectomy (MILP) has become the preferred approach to treat lesions of the pancreatic body and tail. However, the procedure may require conversion to open surgery, with reported conversion rates varying widely in the literature. Th...

Span-Reference and Grounding Reliability in Generative Spanish Clinical Named Entity Recognition: A Validation Study

Generative named entity recognition (NER) systems must identify clinical concepts and map them to exact source spans. We investigated how span-reference design affects this mapping and whether failures arise from recognition or source localisation. Four representation-and-groundi...

Towards Situated Climate Education: Territorial Memory, Climate Justice and Emotional Literacy in Teacher Education (TEJA Model)

Climate change education has expanded in curricular, institutional and media arenas, yet it still faces a central challenge: turning scientific knowledge into educational practices that transform perceptions, decisions and participation. This article argues that the challenge can...

Association between risk of eating disorders and an unhealthy lifestyle score in university students: uniHcos project

Introduction The first year of university is a critical period for the consolidation of lifestyle habits and has been associated with an increased risk of developing eating disorders (EDs). This study aimed to assess the prevalence of ED risk among first-year Spanish university s...

Fibroblast-like Synoviocytes as Therapeutic Targets in Rheumatoid Arthritis: Current Evidence on DMARD-Mediated Modulation

Background/Objectives: Fibroblast-like synoviocytes (FLS) are key contributors to rheumatoid arthritis (RA) pathogenesis, driving synovial inflammation, cartilage degradation, bone erosion and disease persistence. Recent advances have revealed substantial FLS heterogeneity, with...

Burden, perception of stigma, and gender differences among informal care partners of individuals with mild cognitive impairment

Background Caring for individuals with mild cognitive impairment (MCI) is increasingly recognized as a significant clinical challenge. However, the latent burden, driven by perceived stigma and gender-specific vulnerabilities, remains poorly characterized during these early stage...

Barriers and facilitators to advance care planning implementation: a qualitative interprofessional study in the Spanish public health and social care system

Advance Care Planning (ACP) is essential for improving the quality of end-of-life care. Despite having a well-established legal framework, the implementation of ACP in Spain is limited and largely bureaucratic. The existing literature has primarily focused on knowledge deficits a...