University Clinical Centre

Current Perspectives and Effectiveness of Fertility Preservation in Cancer Patients—Data from Serbian National Referral Center

Background/Objectives: Despite numerous fertility-sparing treatments, there are still uncertainties. We present the experience and effectiveness of the oncofertility program from the University Clinical Center of Serbia. Methods: Study included all malignancy patients undergoing...

Association of FOXP3 Gene Polymorphisms with Skin, Vulvar and Ectocervical Squamous Cell Tumors

Background and Objectives: Squamous cell tumors arise from squamous epithelial cells. Polymorphisms in the FOXP3 gene may influence malignancy susceptibility. This study evaluated the potential association of FOXP3 rs3761548 (−3279 A/C) and rs2280883 (IVS9+459 T/C) polymorphisms...

Williams–Campbell syndrome in an adult previously treated as allergic bronchopulmonary aspergillosis: a diagnostic challenge

Abstract Introduction Williams-Campbell Syndrome (WCS) is a rare congenital syndrome of unknown origin, characterized by defective or completely absent bronchial wall cartilage which can lead to distal airway collapse, forming bronchiectasis distal to the collapsed bronchi. The e...

When analgesics are not enough for postpartum perineal pain—a scoping review of the non-pharmacological, conservative therapies

Postpartum perineal pain affects up to 90% of women, with 37% reporting moderate to severe pain. Assisted delivery, episiotomy, and lacerations increase pain and medication use. Management includes pharmacological treatments like paracetamol, opioids, and non-steroidal anti-infla...

CONTEMPORARY IMAGING, ARTHROSCOPIC REPAIR, AND FUNCTIONAL REHABILITATION IN TRAUMATIC TRIANGULAR FIBROCARTILAGE COMPLEX TEARS: A NARRATIVE REVIEW

Traumatic triangular fibrocartilage complex (TFCC) tears are an important cause of ulnar-sided wrist pain, reduced grip strength, restricted forearm rotation, and distal radioulnar joint (DRUJ) instability. Their diagnosis and management remain challenging because morphological a...

Beyond traditional criteria: CRP and fibrinogen as biomarkers of metabolic syndrome in ART-treated people living with HIV and their association with HIF-1α rs11549465

Metabolic syndrome (MS) is highly prevalent among people living with HIV (PLWH) receiving antiretroviral therapy (ART) and is driven by persistent low-grade inflammation. Hypoxia-inducible factor 1 alpha ( HIF-1α ) polymorphisms may influence inflammatory pathways underlying MS....

Integrated Bioinformatic and Experimental Analysis of SLFN11 Expression and Clinical Significance in Locally Advanced Rectal Cancer

Background/Objectives: Schlafen 11 (SLFN11) encodes a DNA damage response protein implicated in sensitivity to DNA-damaging therapies and has been proposed as a predictive biomarker in several malignancies. This study aimed to characterize SLFN11 expression and evaluate its progn...

Mechanical thrombectomy in nonagenarians: real-world outcomes from a highly selected cohort treated at a comprehensive stroke center

Abstract Background Evidence supporting mechanical thrombectomy (MT) in very elderly patients remains limited, as nonagenarians are underrepresented in randomized trials and frequently excluded from MT in routine practice. We evaluated the effectiveness and safety of MT in carefu...