University Clinical Centre

Integrated Bioinformatic and Experimental Analysis of SLFN11 Expression and Clinical Significance in Locally Advanced Rectal Cancer

Background/Objectives: Schlafen 11 (SLFN11) encodes a DNA damage response protein implicated in sensitivity to DNA-damaging therapies and has been proposed as a predictive biomarker in several malignancies. This study aimed to characterize SLFN11 expression and evaluate its progn...

Mechanical thrombectomy in nonagenarians: real-world outcomes from a highly selected cohort treated at a comprehensive stroke center

Abstract Background Evidence supporting mechanical thrombectomy (MT) in very elderly patients remains limited, as nonagenarians are underrepresented in randomized trials and frequently excluded from MT in routine practice. We evaluated the effectiveness and safety of MT in carefu...