University at Buffalo, State University of New York

MOCVD Growth of (011) β-Ga2O3 Films: Defect Control and Device Implication

Abstract β-Ga2O3 is a promising ultrawide-bandgap semiconductor for high-power electronics; however, the realization of thick, low-defect drift layers at high growth rates remains challenging. In this work, metalorganic chemical vapor deposition (MOCVD) growth of (011) β-Ga2O3 dr...

Development-inspired approach for the derivation of functional and transplantable salivary gland organoids from human pluripotent stem cells

Salivary gland (SG) hypofunction significantly affects the life quality of patients with hyposalivation. Current treatment options for these conditions are limited and often result in undesirable side effects. To address this issue, we’ve developed a developmentally inspired stra...

The effect of drysuit diving in warm water on body temperature and post immersion orthostatic hypotension

Introduction: Warm-water diving can limit heat dissipation, particularly when performed in fully encapsulating protective gear, leading to substantial thermal and cardiovascular strain that may impair diver safety. Following immersion, removal of hydrostatic support combined with...

Assessing the environmental benefits of textile waste valorization via methanolysis

The increase in textile production and disposal has contributed to the accumulation of textile waste in the environment. Identifying sustainable methods to valorize PET textile waste can help reduce the environmental impacts associated with this waste stream. Methanolysis is a ch...

Per- and polyfluoroalkyl substances levels other than PFOS, PFOA, or PFHxS and liver cancer risk: a nested case-control analysis

Abstract Epidemiologic studies of PFAS and liver cancer risk have produced conflicting results with no strong or clear associations for pre-diagnostic perfluorooctanesulfonate (PFOS), perfluorooctanoate (PFOA), and perfluorohexanesulfonate (PFHxS). We now report analyses of nine...

A Structural Perspective on Non-covalent Targeting of Conserved Polar Residues in Protein Kinases

Abstract All protein kinases contain conserved amino acid residues that bind the ATP substrate molecule and promote catalysis. As an intensely pursued drug target class, kinase inhibitor development is often streamlined by the utilization of three-dimensional structural data and...

Can Knowledge Counteract Conflict? A Partial Replication Study of PFAS Science Communication

ABSTRACT On the basis of two surveys embedded with a 3 × 2 full‐factorial experiment, we examine whether exposing participants to a message about the process of scientific inquiry prepares them to deal with conflicting risk information more effectively. Study 1 suggests initial e...

Widespread Loss of Heterozygosity and Endoreduplication in Odontogenic Myxoma

Odontogenic myxoma (OM) is an uncommon, locally aggressive odontogenic neoplasm with characteristic histologic and clinico-radiographic features but with potential for histologic overlap with other odontogenic and non-odontogenic entities and a non-specific immunoprofile. Widespr...

Middle-class locations: emplacements and displacements of habitus among the French in London

This article examines the alterations of habitus that lead to feelings of emplacement and displacement among middle-class French citizens living in London. I broaden Bourdieu’s concept of split habitus, developed primarily in the context of social mobility, and extend it to quest...

Death by Triglycerides

A 23-year-old female was found unresponsive after 3 weeks of illness and presented to urgent care a day before her death with a complaint of nausea, vomiting, and abdominal cramping. She had a history of obesity and polyendocrine metabolic ovarian syndrome (PMOS). At autopsy, non...

Epigenetic Regulation of Sialyltransferase ST6GAL1 Drives Breast Tumor Heterogeneity

Background/Objectives: Tumor progression is often accompanied by sialylation of cell-surface N-glycan glycoproteins with α2-6-linked sialic acids by the sialyltransferase ST6GAL1. Moreover, a hallmark of human cancers is heterogeneity in ST6GAL1 expression among cancer cells, yet...

Escherichia coli with penicillin-binding protein 3 insertions: implications for newer β-lactam/β-lactamase inhibitor combinations

ABSTRACT Escherichia coli with penicillin-binding protein 3 (PBP3) insertions appeared in the early 2000s and expanded during the 2010s. The YRIN and YRIK variants predominate globally, while other insertion types remain rare. These insertions frequently co-occur with carbapenema...

2026 International Literacy Association's Timothy and Cynthia Shanahan Outstanding Dissertation Award: An Interview With the Winner

The authors declare no conflicts of interest. Data sharing not applicable to this article as no datasets were generated or analysed during the current study.

Deformable precipitates locally modify fault-mediated plasticity for strength-ductility synergy

Precipitates in structural alloys are conventionally understood as passive obstacles to dislocation motion. Here we show that semi-coherent hexagonal close-packed precipitates in a low-stacking-fault-energy Ni50Co30Ru20 multi-principal element alloy cooperate with planar-fault pl...

The Power to Read and Write/Right to Resist: Literacy Politics from Septima Poinsette Clark

The enduring legacy of Septima Poinsette Clark—teacher-activist, literacy strategist, and warrior of resistance—has been insufficiently researched from a literacy politics perspective. Framing her approach to literacy instruction as acts of political dissent, I center her unwaver...

Innate immune cell-mediated regeneration of acellular vascular grafts in aged hosts

Previously we reported on engineering cell-free vascular grafts that harnessed the potential of the innate immune system to remain patent and regenerate into functional neo-arteries in small and large, preclinical animal models. However, the performance of these grafts in aged ho...

The Meaning of a Cancer Diagnosis for the Rural Patient Through the Lenses of Merleau-Ponty and Heidegger

BACKGROUND: In a rural setting, individuals who receive a cancer diagnosis experience an interconnected group of challenges that contribute to the lived experience of space and time. Philosophers offer a perspective of human experience that provides insight into how individuals m...

Fire, fuel, and climate in the Great Basin from the Middle Holocene to present from the sediments of Blue Lake, NV

Abstract Continuous, high-resolution sedimentary records from the Great Basin are rare. By combining physical sedimentology with charcoal analysis to document changes in lake level and biomass burning, we explore the coevolution of climate and fire ecology over the past 7000 year...

Complement Factor H Regulates a Complement-Extracellular Vesicle-Macrophage Axis in Immune Mediated Kidney Injury

Introduction: Complement Factor H (FH) regulates the alternative complement pathway, and FH deficiency promotes complement activation, macrophage recruitment, and renal injury. Extracellular vesicles (EVs) mediate intercellular communication and may provide molecular signatures o...

Effects of Clear Aligner Therapy on Quality of Life and Anxiety Levels: An Exploratory Study in Patients With Disabilities

INTRODUCTION: Considering the orthodontic needs of individuals with disabilities and the potential impact of such treatments on both quality of life (QoL) and anxiety, this study aims to assess the effects of using clear aligner therapy (Invisalign) on QoL and anxiety levels in t...