Institution
Université Libre de Bruxelles
Recent research
- AI & ComputingOpen access
This paper introduces BSPG-I / FEELLLM, an extended Black Swan PreCog Generator architecture in which early recognition of risk and meaningful felt-state patterns is formalised as dual temporal reasoning: an endogenous longitudinal-memory axis (participant baseline, past self-rep...
- AI & ComputingOpen access
This paper introduces BSPG-I / FEELLLM, an extended Black Swan PreCog Generator architecture in which early recognition of risk and meaningful felt-state patterns is formalised as dual temporal reasoning: an endogenous longitudinal-memory axis (participant baseline, past self-rep...
- Society & EconomicsOpen access
Between-session chasing via time of return in online eCasino gambling
Abstract Background and aims Chasing refers to continuing and/or intensifying gambling following losses (loss-chasing) and/or wins (win-chasing). It is commonly captured between sessions, i.e., returning another day/time after losses or wins in prior sessions. Between-session cha...
- BiologyOpen access
Autism is a complex spectrum disorder for which each individual presents a unique combination of symptoms, strengths, and challenges. The interactions between clinical, environmental, and genetic factors in autism remain an area of ongoing research, with many unresolved questions...
- Health & MedicineOpen access
BACKGROUND: This first part of the S2k guidelines is an update of the 2015 S1 European guidelines based on the structured assessment of clinically relevant topics by the panel of experts. It is complemented by Part 2, which deals with treatments. OBJECTIVES: These guidelines aim...
- BiologyOpen access
Paediatric therapeutic development workshop on osteosarcoma
The fourth Paediatric Therapeutic Development Workshop focused on osteosarcoma, the most common primary bone cancer in children and young adults. Current treatment of osteosarcoma comprises surgery and chemotherapy. Outcome has shown very little improvement over the last four dec...
- Health & MedicineOpen access
Enhancement of cytokine-mediated beta-cell apoptosis by free fatty acids
Type 1 diabetes (T1D) results from dysfunction and loss of the insulin-producing pancreatic β cells. The body’s lipid metabolism is strongly regulated during this process but there is a need to understand how this regulation contributes to the β-cell death. Here, we investigated...
- AI & ComputingOpen access
Bio-inspired decision making in robot swarms under biases
Abstract To operate autonomously, minimal robot swarms must make timely and reliable collective decisions despite noisy individual sensing and severe constraints on communication, computation, and memory. Achieving this capability could expand their use in applications such as he...
- Materials & EnergyOpen access
Total Synthesis of Paliurine E by a Highly Convergent Block Approach
ABSTRACT Macrocycles occupy a privileged position in chemistry, biology and medicine, yet their broader exploitation is curtailed by the lack of general, efficient synthetic strategies. Current approaches to macrocycle construction rely largely on stepwise linear assembly, protec...
- Society & EconomicsOpen access
The bright and dark sides of AI-driven transformation: evidence from Italian firms
Purpose This study examines how firm-level Artificial Intelligence (AI) capabilities are associated with innovation trajectories and firm performance, with particular attention to sustainability-oriented (green) and efficiency-oriented (brown) innovation outcomes. It further inve...
- Health & Medicine
The sweet spot in protein design—Where deep learning meets first principles
This Perspective explores recent methods and prospective ideas for developing hybrid AI-physics-based pipelines for protein and antibody de novo design. We argue that the highest-confidence candidates emerge where deep learning and first-principles models agree, a "sweet spot" th...
- BiologyOpen access
Language trajectories in autism are highly heterogeneous and cannot be captured by unidimensional classifications. Research and clinical practice often rely on verbal/non-verbal or speaking/non-speaking labels, but these categories, when used in isolation, obscure distinct lingui...
- Society & Economics
In recent years, the European Union (EU) has faced mounting challenges in promoting and safeguarding democracy in its neighbourhood, as autocratisation trends, entangled with intensifying geopolitical competition, have progressively reshaped the conditions under which EU democrac...
- Biology
Oligogenic inheritance in epilepsy: A systematic exome‐wide analysis
Abstract Objective Genetic factors contribute to the majority of epilepsies, but the exact genetic cause remains unknown in most patients. Incomplete penetrance and variable expressivity are frequent, and recent studies showed a burden of deleterious variants in epilepsy genes, s...
- Health & MedicineOpen access
Background and Clinical Significance: Steroid cell tumours of the ovary, not otherwise specified (SCT-NOSs), are rare sex cord–stromal neoplasms with a poorly characterised molecular landscape, in which only exceptional CTNNB1 mutations have so far been reported and no recurrent...
- Health & MedicineOpen access
Vancomycin optimised dosing regimens for critically ill patients receiving renal replacement therapy
Optimal dosing of vancomycin in critically ill patients receiving renal replacement therapy (RRT) is uncertain due to high pharmacokinetic variability. We aimed to develop individualised vancomycin dosing recommendations that optimise efficacy while minimising toxicity. Prospecti...